Prediction of Hemodynamic Reactivity During General Anesthesia Using Analgesia/Nociception Index (ANI)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-05-31

Study Completion Date

2013-11-30

Brief Summary

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The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing ear-nose-throat or lower limb orthopedic surgery on desflurane/remifentanil general anesthesia.

Detailed Description

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Measurement of analgesia/nociception index at different time points during procedure and assessment of analgesia/nociception index to predict hemodynamic reactivity by building receiver observer's characteristic curve.

Conditions

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Anesthesia

Keywords

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Analgesia/nociception index Desflurane Remifentanil Orthopedic surgery Ear-nose-throat surgery Hemodynamic reactivity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age 18-75 years
* Ear-nose-throat or lower limb surgery
* General anesthesia using desflurane and remifentanil

Exclusion Criteria

* Age \<18 yrs or \>75 yrs
* Arrythmia
* Preoperative use of B-blockers
* Administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes
* Psychiatric diseases
* Autonomic nervous system disorders (epilepsy)

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Emmanuel Boselli

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Emmanuel Boselli, MD, PhD

Role: STUDY_DIRECTOR

Hôpital Edourd Herriot

Bernard Allaouchiche, MD, PhD

Role: STUDY_CHAIR

Hôpital Edouard Herriot

Locations

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Hôpital Édouard Herriot, HCL

Lyon, Rhône, France

Site Status

Countries

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France

References

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Boselli E, Daniela-Ionescu M, Begou G, Bouvet L, Dabouz R, Magnin C, Allaouchiche B. Prospective observational study of the non-invasive assessment of immediate postoperative pain using the analgesia/nociception index (ANI). Br J Anaesth. 2013 Sep;111(3):453-9. doi: 10.1093/bja/aet110. Epub 2013 Apr 16.

Reference Type BACKGROUND

PMID: 23592690 (View on PubMed)

Other Identifiers

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CPP 2013-021B

Identifier Type: -

Identifier Source: org_study_id