Factors Influencing Anesthetic Drug Requirement

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

3278 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-05-04

Study Completion Date

2017-07-31

Brief Summary

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The main objective of the study is to analyze the influence of several environmental (i.e., timing: seasonal, circadian) and demographic conditions (i.e., age, gender, menstrual cycle) on anesthetic drug requirements (hypnotic and opiate).

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Detailed Description

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Conditions

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Anesthesia, General

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Closed loop anesthesia

Group Type EXPERIMENTAL

Closed loop anesthesia

Intervention Type DEVICE

Propofol and Remifentanil are administered automatically using a closed-loop system

Interventions

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Closed loop anesthesia

Propofol and Remifentanil are administered automatically using a closed-loop system

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing scheduled surgery under general anesthesia, agreeing to participate in the study

Exclusion Criteria

* Age under 18 years
* Pregnancy, breastfeeding woman
* Allergy to propofol, soybeans or peanuts
* Allergy to sufentanil, remifentanil, morphine,
* Allergy to a muscle relaxant or to any of its excipients
* Known hypersensitivity to sufentanil, remifentanil, or to other derivates of fentanyl
* History of central neurological disorder or brain injury
* Patient with dementia
* Patient with pacemaker
* Patient receiving psychotropic drugs or morphine agonist-antagonists
* Surgery on the skull and/or operating position preventing the use of a bispectral index sensor in suitable conditions

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No