Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)

NCT ID: NCT03846908

Last Updated: 2021-09-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-01

Study Completion Date

2021-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Postprandial lipid metabolism will be evaluated in patients with hypertriglyceridemia and normo-lipidemic controls; different fats will be used (saturated fatty acids, mon-unsaturated fatty acids and medium chain fatty acids) for the oral fat challenge.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypertriglyceridemia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

MCT

subjects start with MCT fat load

Group Type EXPERIMENTAL

MCT

Intervention Type OTHER

patients will receive fat load with MCT

SFA

Intervention Type OTHER

patients will receive fat load with SFA

MUFA

Intervention Type OTHER

patients will receive fat load with MUFA

SFA

subjects start with SFA fat load

Group Type EXPERIMENTAL

MCT

Intervention Type OTHER

patients will receive fat load with MCT

SFA

Intervention Type OTHER

patients will receive fat load with SFA

MUFA

Intervention Type OTHER

patients will receive fat load with MUFA

MUFA

subjects start with MUFA fat load

Group Type EXPERIMENTAL

MCT

Intervention Type OTHER

patients will receive fat load with MCT

SFA

Intervention Type OTHER

patients will receive fat load with SFA

MUFA

Intervention Type OTHER

patients will receive fat load with MUFA

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

MCT

patients will receive fat load with MCT

Intervention Type OTHER

SFA

patients will receive fat load with SFA

Intervention Type OTHER

MUFA

patients will receive fat load with MUFA

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* hypertriglyceridemia (150 mg/dl-900 mg/dl)

Exclusion Criteria

* Lipid lowering drugs or indication for Lipid lowering drugs
* LDL-cholesterol \> 190 mg/dl
* Diabetes mellitus
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ludwig-Maximilians - University of Munich

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Klaus Parhofer

Professor of Endocrinology and Metabolism

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University Munich

Munich, , Germany

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

MCT-HTG

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.