Determination of the Optimal Nutrient Mix to Acutely Increase Plasma Ketones
NCT ID: NCT06511206
Last Updated: 2025-04-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
11 participants
INTERVENTIONAL
2024-08-08
2025-03-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Effect of Butter & MCT Oil on Lipoproteins - A RCT
NCT02611102
The Effect of Fatty Acid Composition on Energy Intake and Satiety
NCT00242021
Ketogenic Diet in Healthy Adults With Differing BMI
NCT06515912
Fatty Acid Modulation of Brain Function in Older Adults
NCT06192407
Effects of Meal Macronutrients on Postprandial Lipids
NCT07313787
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
PREVENTION
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
25g MCT-based nutrient mix
25g MCT-based nutrient mix
The 25g MCT-based nutrient mix will be consumed two hours after breakfast.
25g MCT-based nutrient mix + cofactors
25g MCT-based nutrient mix + cofactors
The 25g MCT-based nutrient mix + cofactors will be consumed two hours after breakfast.
non-ketogenic control
non-ketogenic control
The non-ketogenic control will be consumed two hours after breakfast.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
25g MCT-based nutrient mix
The 25g MCT-based nutrient mix will be consumed two hours after breakfast.
25g MCT-based nutrient mix + cofactors
The 25g MCT-based nutrient mix + cofactors will be consumed two hours after breakfast.
non-ketogenic control
The non-ketogenic control will be consumed two hours after breakfast.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Body mass index (BMI) 25-35 kg/m2
* Stable dietary habits (no weight loss or gain \> 5 kg in the past 3 months)
* Participants are able to provide signed and dated written informed consent prior to any study specific procedures
Exclusion Criteria
* Pre-diabetes based on one or a combination of the following criteria:
* ImpairedFastingGlucose(IFG):Fasting plasma glucose ≥ 6.1mmol/l and ≤ 6.9 mmol/l.
* HbA1c of 5.7-6.4%.
* Participants with active congestive heart failure and/or severe renal and or liver insufficiency
* Uncontrolled hypertension
* Alcohol consumption of \> 3 servings per day for man and \> 2 servings per day for woman
* Unstable body weight (weight gain or loss \> 5 kg in the last 3 months)
* Previous enrolment in a clinical study with an investigational product during the last 3 months or as judged by the investigator which would possibly hamper our study results
* Significant food allergies/intolerance (seriously hampering study meals)
* Participants who do not want to be informed about unexpected medical findings
* Blood donation during or within 2 months prior to the study
60 Years
80 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Maastricht University Medical Center
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Joris Hoeks, Dr.
Role: PRINCIPAL_INVESTIGATOR
Maastricht University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Maastricht University
Maastricht, , Netherlands
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
NL86023.068.23
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.