Effects of Coffee Consumption on Health Among Adults

NCT ID: NCT03817944

Last Updated: 2025-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

156 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-18

Study Completion Date

2021-12-31

Brief Summary

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The purpose of this study is to research the changes of typical thermal processing food intervention on health outcome, metabolites, and gut microbiota, in order to explore the molecular mechanism of interaction between maillard reaction associated hazards and complex food matrix, and provide scientific basis and reference model for combining food nutrition and safety protection.

Detailed Description

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Conditions

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Health

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Warm Water

300 mL Warm Water per day for 8 weeks

Group Type PLACEBO_COMPARATOR

Warm Water

Intervention Type OTHER

300 mL Warm Water per day for 8 weeks

Caffeinated Coffee

300 mL Caffeinated Coffee per day for 8 weeks

Group Type EXPERIMENTAL

Caffeinated Coffee

Intervention Type OTHER

300 mL Caffeinated Coffee per day for 8 weeks

Decaffeinated Coffee

300 mL Decaffeinated Coffee per day for 8 weeks

Group Type EXPERIMENTAL

Decaffeinated Coffee

Intervention Type OTHER

300 mL Decaffeinated Coffee per day for 8 weeks

Interventions

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Warm Water

300 mL Warm Water per day for 8 weeks

Intervention Type OTHER

Caffeinated Coffee

300 mL Caffeinated Coffee per day for 8 weeks

Intervention Type OTHER

Decaffeinated Coffee

300 mL Decaffeinated Coffee per day for 8 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Non-smoking, non-occupational exposed healthy volunteers, 18.5\<BMI\<30 kg/m\^2, were screened. If the evaluation of disease history, blood biochemistry and blood routine was normal, the volunteers were considered healthy.
Minimum Eligible Age

17 Years

Maximum Eligible Age

29 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Yu Zhang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Zhejiang university

Hangzhou, , China

Site Status

Countries

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China

Other Identifiers

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RCT-Coffee

Identifier Type: -

Identifier Source: org_study_id

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