Role of Colonic Events on Metabolism and Appetite Control: A Synbiotic Approach

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-09-30

Study Completion Date

2012-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the study is to evaluate food factors related to colonically derived regulation of glucose metabolism (and related parameters) and satiety using a semi-acute meal study in healthy subjects as experimental model.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effects of Dietary Fibre on Glucose Metabolism and Satiety

NCT02093481

Obesity Metabolic Syndrome

COMPLETED EARLY_PHASE1

Over-night Effect of Dietary Fiber on Glucose Metabolism and Satiety

NCT02347293

Obesity Metabolic Syndrome

COMPLETED EARLY_PHASE1

Metabolic Effect of New Foods Through Gut-brain Axis

NCT01851304

Obesity Overweight

COMPLETED NA

Effect of Very-low Calorie Diet and Synbiotic Supplementation in Gut Microbiota (Pronokal Method)

NCT03530501

Weight Loss Inflammation

COMPLETED NA

Intake of Beta-glucan and Postprandial Regulation of Blood Glucose Metabolism in Healthy Subjects

NCT03293693

Post Prandial Blood Glucose Gut Microbiota Satiety

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Obesity Metabolic Syndrome

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

+ ind.CHO + prebiotics

test meal: intrinsic indigestible carbohydrates in combination with a combined probiotic supplement.

Group Type EXPERIMENTAL

test meal

Intervention Type OTHER

+ ind.CHO - prebiotics

test meal: intrinsic indigestible carbohydrates in combination with placebo probiotic supplement.

Group Type EXPERIMENTAL

test meal

Intervention Type OTHER

- ind.CHO - prebiotics

reference: no ind. carbohydrates and no probiotic supplement

Group Type EXPERIMENTAL

reference

Intervention Type OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

test meal

Intervention Type OTHER

reference

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Normal fasting blood glucose, BMI 19-25 kg/m2, for women: hormon based contraceptives

Exclusion Criteria

* gastrointestinal diseases or food allergies e.g. lactose-, gluten intolerance, metabolic disorders e.g. diabetes, tobacco/snuff users. Antibiotic or probiotic usage within two weeks, and during the study. Vegetarians

Minimum Eligible Age

20 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes