The Combined Effect of Dairy and Exercise on Bone and Inflammation
NCT ID: NCT03615989
Last Updated: 2021-05-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
TERMINATED
NA
13 participants
INTERVENTIONAL
2018-10-01
2020-03-14
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Bone and Inflammatory Outcomes - Nutrition and Exercise Trials
NCT06041087
The Effect of Dairy and Dairy-Free Alternative Beverages on Post-Exercise Anabolism in Active Youth
NCT05827666
Effects of Increased Greek Yogurt Consumption in Youth and Young Adult Athletes
NCT05922462
Dairy vs Plant-based Beverages for Improving Bone Health During Exercise
NCT06946316
Brock Exercise And Supplement Trials
NCT03196856
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Design: Randomized controlled crossover trial.
Participants: 13 healthy university aged females.
Methods: Participants were asked to complete 2 different acute exercise and nutritional supplement trials. Each trial will be assigned in random order. The two trials were: 1) exercise+carbohydrate (CHO), and 2) exercise+milk (Milk). The whole study, per participant, took a maximum of 8-12 weeks to complete as each supplement trial was separated by \~4 weeks. Each treatment is outlined below.
\*\*\*\*\*\*DUE TO COVID-19, we removed the treatment trial which involved milk+creatine supplementation. Despite randomization, and before the trial was closed, only 11 participants completed this trial\*\*\*\*\*\*\*\*
Anticipated Results: The investigators anticipate that dairy and exercise will have a greater positive impact on acute bone cell activity and inflammation in healthy young females compared to exercise and CHO.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
PREVENTION
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Exercise and Carbohydrate (CHO)
Participants had a fasted, baseline blood sample (10ml) taken upon arrival to the lab. They then completed a supervised resistance and plyometric exercise bout. Immediately following exercise, 50g of carbohydrate (maltodextrin) + water was consumed. Two more blood samples followed the exercise bout at 5 minutes post (10ml) and 1 hour post (10ml). An additional 50g of carbohydrate was consumed with water 1 hour post exercise. Two more fasting blood samples (10ml) were taken 24 and 48 hours later.
Resistance and Plyometric Exercise
A single resistance and plyometric exercise bout per trial.
Carbohydrate (Maltodextrin powder mixed with water)
50 grams immediately after exercise bout. 50 grams 1 hour after exercise bout.
Exercise and Milk (Milk)
Participants had a fasted, baseline blood sample (10ml) taken upon arrival to the lab. They then completed a supervised resistance and plyometric exercise bout. Immediately following exercise, \~500 ml of skim milk was consumed. Two more blood samples followed the exercise bout at 5 minutes post (10ml) and 1 hour post (10ml). An additional 500 ml of skim milk was consumed 1 hour post exercise. Two more fasting blood samples (10ml) were taken 24 and 48 hours later.
Resistance and Plyometric Exercise
A single resistance and plyometric exercise bout per trial.
Skim Milk
500 ml immediately after exercise bout. 500 ml 1 hour after exercise bout.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Resistance and Plyometric Exercise
A single resistance and plyometric exercise bout per trial.
Carbohydrate (Maltodextrin powder mixed with water)
50 grams immediately after exercise bout. 50 grams 1 hour after exercise bout.
Skim Milk
500 ml immediately after exercise bout. 500 ml 1 hour after exercise bout.
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Normal BMI (18.5-24.9) kg/m2
* Low to moderately physically active (0-2 times/week)
* No allergy to dairy protein or lactose intolerance
* On no medication related to a chronic condition
* On birth control (or not but with regular mensural cycle)
18 Years
30 Years
FEMALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Brock University
OTHER
York University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Andrea Josse
Assistant Professor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Andrea R Josse, PhD
Role: PRINCIPAL_INVESTIGATOR
York University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
York University
Toronto, Ontario, Canada
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
REB 17-402
Identifier Type: OTHER
Identifier Source: secondary_id
2019-045
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.