Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2018-03-13
2018-12-11
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
QUADRUPLE
Study Groups
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Placebo
Placebo
Placebo
Reconstituted in water and given to subjects
43.3 mg hydrolyzed green coffee extract
hydrolyzed green coffee extract as interventions
43.3 mg hydrolyzed green coffee extract
Reconstituted in water and given to subjects
86.6 mg hydrolyzed green coffee extract
hydrolyzed green coffee extract as interventions
86.6 mg hydrolyzed green coffee extract
Reconstituted in water and given to subjects
173 mg hydrolyzed green coffee extract
hydrolyzed green coffee extract as interventions
173 mg hydrolyzed green coffee extract
Reconstituted in water and given to subjects
Interventions
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43.3 mg hydrolyzed green coffee extract
Reconstituted in water and given to subjects
86.6 mg hydrolyzed green coffee extract
Reconstituted in water and given to subjects
173 mg hydrolyzed green coffee extract
Reconstituted in water and given to subjects
Placebo
Reconstituted in water and given to subjects
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Willing and able to sign written informed consent prior to trial entry
* Healthy as determined by the medical history and physical examination
Exclusion Criteria
* Current smokers
* Abnormal blood pressure as defined as follow: systolic \<90 or \>140 mmHg and diastolic \<60 or \>90 mmHg
* Regular consumption of cholesterol-lowering medication
* Regular consumption of antihypertensive medication
* Regular consumption of any vasoactive medication that cannot be discontinued for at least 4 half-lives before the FMD assessment
* Any food allergies
* Any intakes of multivitamin-tablets and other supplemental compounds 10 days before the study start and throughout the study
* Inability to refrain from coffee/tea and alcohol consumption for 12 h prior to study visits
* Acute or chronic major psychiatric illness or other major illness that in the opinion of the investigator would make the subjects' participation in the study unsafe or prevent them from fully complying with the study procedures
* Body mass index (BMI) outside 18-32 kg/m2 range
45 Years
65 Years
ALL
Yes
Sponsors
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Société des Produits Nestlé (SPN)
INDUSTRY
Responsible Party
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Principal Investigators
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Leslie Tan
Role: STUDY_CHAIR
Société des Produits Nestlé (SPN)
Locations
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University of Western Australia
Crawley, Perth, Australia
Countries
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Other Identifiers
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1717NRC
Identifier Type: -
Identifier Source: org_study_id
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