Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
NOT_YET_RECRUITING
PHASE2
40 participants
INTERVENTIONAL
2026-03-31
2030-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Participants will:
* give two blood draws of 5 mL each
* have a camera placed under the tongue to take pictures of blood vessels
* have 2 laser Doppler microdialysis catheters placed on the forearm to monitor blood vessels before and after local drug infusion
Researchers will compare blood vessel function of those who take estrogen supplements to those who do not.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Effects of Quercetin on Cardiometabolic Outcomes
NCT06230861
Flavonoids, Blood Pressure and Blood Vessel Function
NCT01530893
Biological Effects of Quercetin in COPD Phase II
NCT06003270
Effects of Oral Antioxidant Cocktail in Cardiovascular Disease Patients
NCT03629613
Biological Effects of Quercetin in COPD
NCT03989271
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
BASIC_SCIENCE
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Use of oral quercetin to improve human microvascular function
Quercetin is a non-FDA approved, over-the-counter supplement that has been shown to improve oxidative capacity in blood vessels.
Quercetin (dietary supplement)
Quercetin will be provided to take one Quercetin per day for 30 days to look for differences in microvascular function.
Placebo
A placebo will be administered for 30 days followed by assessment of the subject's microvascular function.
Placebo
Subjects randomized to receive placebo will be administered a standard placebo sugar pill.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Quercetin (dietary supplement)
Quercetin will be provided to take one Quercetin per day for 30 days to look for differences in microvascular function.
Placebo
Subjects randomized to receive placebo will be administered a standard placebo sugar pill.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Aged 18-40 years
* English Speaking
Exclusion Criteria
* Resting SBP ≥180 mmHg or DBP ≥ 110mmHg
* Pregnancy or breastfeeding.
* Prior history of myocardial infarction
* Diagnosis of more than 1 risk factor for coronary artery disease (active smoker, diabetes mellitus- type 1 or 2, congestive heart failure, hyperlipidemia, hypertension)
* Active mouth sores that affect the buccal mucosa.
18 Years
40 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Medical College of Wisconsin
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Julie K. Freed
Executive Vice Chair
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Froedtert Hospital
Wauwatosa, Wisconsin, United States
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
PRO00053081
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.