Markers in Follicular Fluid and in Embryo Culture Medium as a Marker of Oocyte and Embryo Quality

NCT ID: NCT03350009

Last Updated: 2019-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

220 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-11

Study Completion Date

2019-11-30

Brief Summary

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Assessment of the quality of follicular fluid and early embryo via chemical markers.

Detailed Description

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The selectin of an embryo for transfer is currently based on detailed morphological assessment and scoring system. morhpokinetics introduced recently to IVF laboratories can define annotations and provide an algorithm for optimal cleavage rates and embryonic development. however more data and validations are requested when it comes to choosing the best single embryo from a cohort of available similarly graded embryos. Consequently, non-invasive quantitative methods for embryo selection prior to transfer have been sought. In the current study metabolic profile of follicular fluid and the embryos produced in IVF procedure will be assessed

Conditions

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Infertility/Sterility

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Study Groups

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High and low grade embryos

The distribution for the high and low grade embryos is based on common morphological grading criteria.

No interventions assigned to this group

High and low quality follicles

The distribution for the high and low grade oocytes is based on common morphological grading criteria and on different features of the participants such as age.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing IVF procedures at Carmel Medical Center and are able to sign an informed consent form.
* Female patients age 18-45

Exclusion Criteria

* Women with any malignancy
* Patient's request to be withdrawn from the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Carmel Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Martha Direnfeld, Prof.

Role: PRINCIPAL_INVESTIGATOR

Carmel Medical Center

Locations

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Carmel Medical Center

Haifa, , Israel

Site Status

Countries

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Israel

Other Identifiers

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CMC-16-0163-CTIL

Identifier Type: -

Identifier Source: org_study_id

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