Egg Quality Assessment

NCT ID: NCT06609421

Last Updated: 2025-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

SUSPENDED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-10-09

Study Completion Date

2027-02-01

Brief Summary

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The goal of this observational study is to learn about egg physiology in humans.

The main question it aims to answer is if there is an association between egg physiology and egg quality.

Discarded, unfertilised eggs and follicular fluid collected during routine egg retrieval from participants undergoing in vitro fertilisation (IVF) as part of their regular medical care along with information from participants' electronic medical records will be collected and analysed.

Detailed Description

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Conditions

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Infertility (IVF Patients) Ovarian Aging IVF

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Control Group

Women undergoing in-vitro fertilisation (IVF) with male factor diagnoses.

Informative Appointment

Intervention Type OTHER

The only intervention involving the participants is non-clinical, which is an extra 30-minute informative telephone appointment added to the standard care consultation schedule of interested IVF patients where they will be presented with a digital consent PDF form to sign by a study nurse or clinically trained research personnel. Participants will be in the study for 24-30 months. During this time their discarded, unfertilised oocytes and follicular fluid collected during routine oocyte retrieval along with information from their electronic medical records will be collected and analysed.

Case Group

Women undergoing IVF with a diagnosis other than male factor.

Informative Appointment

Intervention Type OTHER

The only intervention involving the participants is non-clinical, which is an extra 30-minute informative telephone appointment added to the standard care consultation schedule of interested IVF patients where they will be presented with a digital consent PDF form to sign by a study nurse or clinically trained research personnel. Participants will be in the study for 24-30 months. During this time their discarded, unfertilised oocytes and follicular fluid collected during routine oocyte retrieval along with information from their electronic medical records will be collected and analysed.

Interventions

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Informative Appointment

The only intervention involving the participants is non-clinical, which is an extra 30-minute informative telephone appointment added to the standard care consultation schedule of interested IVF patients where they will be presented with a digital consent PDF form to sign by a study nurse or clinically trained research personnel. Participants will be in the study for 24-30 months. During this time their discarded, unfertilised oocytes and follicular fluid collected during routine oocyte retrieval along with information from their electronic medical records will be collected and analysed.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Undergoing in vitro fertilisation treatment or egg freezing

Exclusion Criteria

* No discarded, unfertilised eggs for collection
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ovom Care GmbH

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Avenues Clinic

London, , United Kingdom

Site Status

Countries

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United Kingdom

References

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Brayboy LM, Oulhen N, Witmyer J, Robins J, Carson S, Wessel GM. Multidrug-resistant transport activity protects oocytes from chemotherapeutic agents and changes during oocyte maturation. Fertil Steril. 2013 Nov;100(5):1428-35. doi: 10.1016/j.fertnstert.2013.07.002. Epub 2013 Aug 13.

Reference Type BACKGROUND
PMID: 23953328 (View on PubMed)

Other Identifiers

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340652

Identifier Type: -

Identifier Source: org_study_id

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