Study of Free DNA Content of Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment

NCT ID: NCT02480491

Last Updated: 2015-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2015-05-31

Brief Summary

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Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in intra cytoplasmic sperm injection Treatment Cycles.

Detailed Description

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The aim of the present study is to determine whether cell free DNA content of the culture medium of the human embryo correlates with the quality and reproductive potential of embryos in ICSI cycles and, thus, to look for a new non invasive tool of assessing embryo quality beside morphological assessment. Determining a rapid, noninvasive method for the assessment of the developmental potential of embryos may be a great achievement

Conditions

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Infertility

Study Design

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Observational Model Type

COHORT

Study Groups

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Third day embryos

embryos culture media during third day after fertilization

measuring cell freeDNA

Intervention Type OTHER

measuring cell free DNA using PCR

Fifth day embryos

embryos culture media during fifth day after fertilization

measuring cell freeDNA

Intervention Type OTHER

measuring cell free DNA using PCR

Interventions

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measuring cell freeDNA

measuring cell free DNA using PCR

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* third day embryos

Exclusion Criteria

* less than third day embryos
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ain Shams University

OTHER

Sponsor Role collaborator

Sadat City University

OTHER

Sponsor Role lead

Responsible Party

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Azza Awad Abdel Razik Mohamed

Director of Embryology Lab., Ain Shams Univesity

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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SCS-1

Identifier Type: -

Identifier Source: org_study_id

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