Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF

NCT ID: NCT03810040

Last Updated: 2019-01-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

400 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-28

Study Completion Date

2019-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. The participants were divided into two group. Odd-numbered days the zygotes were degranulated with the 140 microns needles. Even-numbered days the zygotes were degranulated with the 150 microns needles. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Embryo

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Odd-numbered days

Once odd-numbered days the zytoges of IVF cycle were collected. The 140 microns denuding pipette was used.

Group Type ACTIVE_COMPARATOR

140 microns denuding pipette

Intervention Type DEVICE

the degranulated needle size was 140 microns

Even-numbered days

Once even-numbered days the zytoges of IVF cycle were collected. The 150 microns denuding pipette was used.

Group Type EXPERIMENTAL

150 microns denuding pipette

Intervention Type DEVICE

the degranulated needle size was 150 microns

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

140 microns denuding pipette

the degranulated needle size was 140 microns

Intervention Type DEVICE

150 microns denuding pipette

the degranulated needle size was 150 microns

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* first cyele of IVF treatment

Exclusion Criteria

* oocyte number less than 4
* oocyte number over than 25
Minimum Eligible Age

22 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Tang-Du Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

jin ni

Role: STUDY_DIRECTOR

Tang-Du Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Tangdu Hospital

Xi'an, Shaanxi, China

Site Status

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

wang ming

Role: CONTACT

8613259809290

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

wang ming

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

123456

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Selection of Embryos by Time-lapse
NCT01138631 COMPLETED NA