Triggering Ovulation at Follicle Size Smaller or Larger Than 17mm in a Modified Natural Cycle
NCT ID: NCT07088952
Last Updated: 2026-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
572 participants
INTERVENTIONAL
2025-10-22
2028-05-30
Brief Summary
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This prospective randomized study seeks to address this knowledge gap by evaluating the non-inferiority of triggering ovulation in mNC with follicle diameters of 13-16.9mm compared to the conventional 17-22mm.
The study aims to enhance the understanding of the impact of follicle size at ovulation in reproductive outcomes, optimize FET treatments providing a more flexible mNC protocol, and improve patient care in ART clinics.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Control
Trigger indicated as per standard clinical practice at folicular diameter of at least 17mm
No interventions assigned to this group
Early trigger
Trigger indicated at folicular diameter smaller than standard clinical practice
Trigger at smaller folicular size
Trigger indicated at folicular diameter smaller than standard clinical practice, from 13mm to 16.9mm
Interventions
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Trigger at smaller folicular size
Trigger indicated at folicular diameter smaller than standard clinical practice, from 13mm to 16.9mm
Eligibility Criteria
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Inclusion Criteria
* Spontaneous menstrual cycles
* Consent to undergo frozen embryo transfer in a modified natural cycle
Exclusion Criteria
* Fluid in endometrial cavity
18 Years
50 Years
FEMALE
No
Sponsors
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Vida Recoletas Sevilla
OTHER
Responsible Party
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Locations
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Vida Recoletas Sevilla
Seville, Sevilla, Spain
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2310-SEV-02-MF
Identifier Type: -
Identifier Source: org_study_id
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