Embryo Implantation After Induced Endometrial Injury

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

600 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2022-11-21

Brief Summary

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Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure.

The purpose of this study is to determine whether the induced endometrial injury could be beneficial for regular patients undergoing IVF

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Detailed Description

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Endometrial induced injury has been suggested that could improve embryo implantation in cases of patients with recurrent implantation failure. The mechanisms that induce that improvement remain unknown.

We want to analyse if the endometrial induce injury could be useful in cases of standard patients who require assisted reproductive techniques.

For that purpose we will start a randomized controlled trial with the ideal background in implantation in ART, the egg donation programme.

Conditions

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Sterility

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Scratching

induced endometrial injury

Group Type EXPERIMENTAL

Scratching

Intervention Type PROCEDURE

Endometrial biopsy

No scratching

None intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Scratching

Endometrial biopsy

Intervention Type PROCEDURE

Other Intervention Names

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Endometrial induced injury

Eligibility Criteria

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Inclusion Criteria

* 19-44 aged women
* 19-29.9 Kg/m2.
* 1st or 2nd fresh embryo transfer ( egg donation).
* 1 or 2 blastocysts available.
* written agreement.
* \> or = 6 mms endometrial thickness.