Endometrial Scratching for Cryopreserved Embryo Transfer

NCT ID: NCT02093442

Last Updated: 2018-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

62 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-31

Study Completion Date

2016-06-30

Brief Summary

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Endometrial injury performed in a cycle preceding the one for embryo transfer is associated with an increased implantation and pregnancy rate when carried out during the month preceding that of ovulation induction and fresh embryo transfer. However, there is no evidence about the effect of this intervention on the transfer of cryopreserved embryos.

Detailed Description

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Conditions

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Subfertility

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Endometrial injury

Women allocated to this group will be submitted to endometrial injury before undergoing endometrial preparation for embryo transfer.

Group Type EXPERIMENTAL

Endometrial injury

Intervention Type PROCEDURE

Endometrial biopsy using a pipelle de Cornier

Control

Women allocated to this group will NOT be submitted to endometrial injury before undergoing endometrial preparation for embryo transfer.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Endometrial injury

Endometrial biopsy using a pipelle de Cornier

Intervention Type PROCEDURE

Other Intervention Names

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Endometrial scratching

Eligibility Criteria

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Inclusion Criteria

* Age \> 18
* At least one cryopreserved embryo

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

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Wellington P Martins, MD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Wellington P Martins, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Locations

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Setor de Reprodução Humana - FMRP-USP

Ribeirão Preto, São Paulo, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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CAAE:03292412.0.0000.5440

Identifier Type: -

Identifier Source: org_study_id

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