Saturated Fatty Acids Intake and Mortality, Diabetes, Hypertension and Overweight

NCT ID: NCT03281512

Last Updated: 2024-03-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

14383 participants

Study Classification

OBSERVATIONAL

Study Start Date

1989-01-01

Study Completion Date

2012-12-31

Brief Summary

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The role of saturated fatty acids (SFAs) intake in the development of total death, cardiovascular diseases, diabetes, hypertension and overweight are in great controversy but evidence from large population in China is scant.The investigators aim to use the data from the China Health and Nutrition Survey to assess the long-term association of SFAs intake with total mortality, diabetes, hypertension and overweight.

Detailed Description

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The role of saturated fatty acids (SFAs) intake in the development of total death, diabetes, hypertension and overweight are in great controversy but evidence from large population in China is lacking.The investigators aim to utilize the data from the China Health and Nutrition Survey. The investigators will calculate the cumulative average intake of SFAs based on 3 consecutive 24-h dietary recalls in each round.Sex-specific Cox regression models will be used to estimate the relative risk.Results from our work will be used to provide epidemiological evidence for improving recommendation on SFAs intake for Chinese in dietary guidelines.

Conditions

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Morality Diabetes Hypertension Overweight

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Adults aged ≥20 with complete data on diet and follow-up time

Exclusion Criteria

* Cardiovascular diseases
* Diabetes (for analyses of diabetes)
* Body mass index ≥ 24 kg/㎡ (for analyses of overweight)
* Hypertension (for analyses of hypertension)
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute of Health and Nutrition

OTHER_GOV

Sponsor Role collaborator

Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Jingjing Jiao

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Zhuang P, Cheng L, Wang J, Zhang Y, Jiao J. Saturated Fatty Acid Intake Is Associated with Total Mortality in a Nationwide Cohort Study. J Nutr. 2019 Jan 1;149(1):68-77. doi: 10.1093/jn/nxy237.

Reference Type DERIVED
PMID: 30608597 (View on PubMed)

Other Identifiers

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Cohort_SFA

Identifier Type: -

Identifier Source: org_study_id

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