Type of Dietary Fat Intakes in Relation to Mortality in US Adults: An Iso-caloric Substitution Analysis From the American National Health and Nutrition Examination Survey Linked to the US Mortality Registry
NCT ID: NCT03220139
Last Updated: 2017-07-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
18372 participants
OBSERVATIONAL
1999-01-01
2017-01-01
Brief Summary
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Objective The aim of the present study was to estimate the mortality risk reduction related to a dietary change from saturated fat to an equal amount of mono or polyunsaturated fat intake.
Design The American National health and nutrition examination surveys conducted between 1999 and 2010 were linked to the 2011 national US death registry resulting in an observational prospective mortality study. Proportional hazards Cox models were used to evaluate the association between saturated, mono-unsaturated and poly-unsaturated fat with all-cause, and cause specific mortality. Substitution analysis was conducted to estimate an iso-caloric substitution of 10% of the energy from dietary fat intake applied to the substitution of saturated fat with an equal amount of energy from mono-unsaturated or poly-unsaturated fat.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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fat intake
Observational study on fat intake and mortality
Eligibility Criteria
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Inclusion Criteria
* age \>= 30 years old
Exclusion Criteria
* Cancer, type-II diabetes, cardiovascular disease at baseline
* Missing data on covariates used in the model
30 Years
85 Years
ALL
No
Sponsors
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North-West University, South Africa
OTHER
Responsible Party
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Cristian Ricci
Dr
Other Identifiers
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XXXX1
Identifier Type: -
Identifier Source: org_study_id
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