Conditioned Pain Modulation Using Painful Cutaneous Electrical Stimulation or Simply Habituation?

NCT ID: NCT03237650

Last Updated: 2017-08-02

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 33 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2016-04-30
• Study Completion Date: 2016-09-30

Brief Summary

Painful cutaneous electrical stimulation (PCES) and corresponding evoked potentials led to a significant pain relief and decrease of evoked potentials and has been used to analyze conditioned pain modulation (CPM). However, it is unknown whether the pain relief results from habituation to the repeated painful electric stimulation. We compared the effects of CPM and habituation on PCES-induced pain and PCES-evoked potentials and analyzed whether increased attention by a random change of electric intensities amplifies the habituation effects.

Conditions

Habituation

Study Design

• Observational Model Type: CASE_CROSSOVER
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• healthy volunteers

Exclusion Criteria

• any kind of disease

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Ruhr University of Bochum

OTHER

Sponsor Role: lead

Responsible Party

Christoph Maier, Prof. Dr.

Prof. Dr. med.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Christoph Maier, Prof Dr med

Role: PRINCIPAL_INVESTIGATOR

University clinic Bergmannsheil Bochum gGmbH, Department of pain medicine

Other Identifiers

PCES-Hab

Identifier Type: -

Identifier Source: org_study_id