Modulation of Painful Perception

NCT ID: NCT02528578

Last Updated: 2017-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-06-30

Study Completion Date

2015-11-30

Brief Summary

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The objective of the study is to evaluate in healthy volunteers, the influence of empathy on pain perception.

It is widely accepted in the clinical management that the feeling of listening to the patients' pain would have a favorable influence on the pain, and conversely, the lack of listening would be aggravating.

In this study, the volunteer will receive painful thermal stimuli in empathetic context (l, empathetic or non-empathetic) Two situations will oppose, one where the examiner neglect or minimize the suffering of the voluntary and the other or the contrary, the subject will receive empathy.

The first part of the project is to verify that the pain is influenced by the empathetic context. The second part will be conducted functional MRI, which should isolate the brain regions affected by other people's empathy for pain.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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healthy volunteers

Group Type EXPERIMENTAL

thermal stimulation delivered by a thermode.

Intervention Type DEVICE

Empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

functional MRI

Intervention Type OTHER

MRI realised with thermal stimulations and empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

Interventions

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thermal stimulation delivered by a thermode.

Empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

Intervention Type DEVICE

functional MRI

MRI realised with thermal stimulations and empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Right handed

Exclusion Criteria

* Pregnant or lactating women,
* Against-indications to MRI
* Drug intake of less than 12 hours,
* Neurological history or deficits, psychiatric, auditory or visual.
* Decline to participate
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Roland PEYRON, MD

Role: PRINCIPAL_INVESTIGATOR

CHU de SAINT-ETIENNE

Locations

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Hospices Civils de LYON

Lyon, , France

Site Status

CHU de SAINT-ETIENNE

Saint-Etienne, , France

Site Status

Countries

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France

Other Identifiers

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2012-A01232-41

Identifier Type: OTHER

Identifier Source: secondary_id

1208141

Identifier Type: -

Identifier Source: org_study_id