3h of PNE on BDNF and Pain Levels

NCT ID: NCT05736172

Last Updated: 2023-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-15

Study Completion Date

2024-11-30

Brief Summary

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The promotion of neuroplasticity in conjunction with strategies for restructuring maladaptive cognitions that largely cause the activation of neural networks that contribute to the perpetuation of pain is therefore a fundamental neurophysiological principle for establishing a neurophysiological basis for pain.

perpetuation of pain, is therefore a fundamental neurophysiological principle for establishing physiotherapy therapeutic to establish therapeutic strategies from physiotherapy that contribute to improve the quality of life of patients with chronic pain. Based on the theory that neurotrophic factors such as BDNF play a fundamental role in the initiation and or maintenance of hyperexcitability of central neurons in pain, we consider that the levels of this neurotrophic factor, such as BDNF, may have an important role in the perpetuation of pain. That the levels of this neurotrophic factor may be modified by the application of a therapeutic education protocol, favoring therapeutic education protocol, favoring a reduction in pain intensity.

Detailed Description

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Conditions

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Chronic Pain Musculoskeletal Pain

Keywords

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bdnf pain neuroscience education

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Pain group education

In this group, the education session will be provided in a face-to-face group setting.

Group Type EXPERIMENTAL

Pain neuroscience grupal education

Intervention Type BEHAVIORAL

The face to face education group will be carried out with a physiotherapist addressing various topics in the neurosciences of pain. In the active control group, information will only be provided in written form for the individual patient to read.

Pain material education

In this group the same education session will be provided in written form by means of a leaflet.

Group Type ACTIVE_COMPARATOR

Pain neuroscience grupal education

Intervention Type BEHAVIORAL

The face to face education group will be carried out with a physiotherapist addressing various topics in the neurosciences of pain. In the active control group, information will only be provided in written form for the individual patient to read.

Interventions

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Pain neuroscience grupal education

The face to face education group will be carried out with a physiotherapist addressing various topics in the neurosciences of pain. In the active control group, information will only be provided in written form for the individual patient to read.

Intervention Type BEHAVIORAL

Other Intervention Names

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Pain neuroscience written education

Eligibility Criteria

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Inclusion Criteria

* males and females aged 18 to 65 years with musculoskeletal pain for a minimum of 3 months
* patients recruited by information pamphlets from the university clinic of the Rey Juan Carlos University, and CSEU La Salle
* ability to perform all the clinical tests and to understand the study process, as well as to obtain informed consent.

Exclusion Criteria

-Systemic, neurological, oncological or inflammatory diseases; psychiatric pathologies, pregnancy, type II diabetes.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidad Rey Juan Carlos

OTHER

Sponsor Role collaborator

Universidad Autonoma de Madrid

OTHER

Sponsor Role lead

Responsible Party

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Raúl Ferrer-Peña

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Silvia Di Bonaventura

Role: PRINCIPAL_INVESTIGATOR

Universidad Rey Juan Carlos

Locations

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Silvia Di Bonaventura

Madrid, , Spain

Site Status RECRUITING

Countries

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Spain

Facility Contacts

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Silvia Di Bonaventura

Role: primary

Other Identifiers

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3HPNEBDNF

Identifier Type: -

Identifier Source: org_study_id