The Influence of Baseline Sensitivity and Expectation on Exercise-induced Hypoalgesia in Young Healthy Adults

NCT ID: NCT03871504

Last Updated: 2019-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

250 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-25

Study Completion Date

2022-12-30

Brief Summary

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The purpose of this study is to investigate the influence of baseline experimental pain sensitivity and expectation on the pain response following a single exercise session. Pain assessment will be done with different intensities of noxious stimuli. In addition, the expectation of how exercise impacts pain will be studied.

Detailed Description

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The relation between baseline pain sensitivity and the pain response following exercise is not clear. The aims of this study are to investigate the influence of baseline experimental pain sensitivity on the pain response following submaximal isometric exercise, and whether expectations would influence outcomes with subsequent exposure to exercise.

Conditions

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Healthy Subjects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

All subjects will participate in two randomized sessions (an exercise session and control session). The exercise session consists of submaximal isometric exercise while the quiet rest session consists of a rest for a period that mimics the time spent in exercise.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
Participants are blinded to the hypothesis of this study.

Study Groups

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submaximal isometric exercise.

submaximal isometric exercise will be performed.

Group Type EXPERIMENTAL

Submaximal isometric exercise

Intervention Type OTHER

The exercise is a submaximal isometric contraction

Quiet rest.

Subject will rest in seating position for a period that mimics the exercise time.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Submaximal isometric exercise

The exercise is a submaximal isometric contraction

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy adults
* English proficiency

Exclusion Criteria

* Acute pain condition
* Chronic pain condition
* Mental health disorder
* Cardiovascular disease
* Any chronic illness
* Difficulty with physical exercise
* Recent surgery
* Pulmonary disease
* Diabetes
* Smoking
* Raynaud disease
* Claustrophobia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Marquette University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marie Hoeger Bement, PT, PhD

Role: PRINCIPAL_INVESTIGATOR

Marquette University

Locations

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Marquette University

Milwaukee, Wisconsin, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Marie Hoeger Bement, PT, PhD

Role: CONTACT

414-288-6738

Facility Contacts

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Marie Hoeger Bement, PT, PhD

Role: primary

Other Identifiers

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HR-2999

Identifier Type: -

Identifier Source: org_study_id

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