Audio-enhanced Analgesia in Healthy Subjects

NCT ID: NCT01835275

Last Updated: 2016-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-06-30

Study Completion Date

2013-04-30

Brief Summary

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The purpose of this study is to determine whether enhanced audio methods can be used to improve analgesia for experimental pain in healthy subjects.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Music conditioning

Subjects are tested with music, sound, and silence, after conditioning to enhance music induced analgesia

Group Type EXPERIMENTAL

Enhanced Audio

Intervention Type BEHAVIORAL

Audio

Intervention Type BEHAVIORAL

Sound

Subjects are tested with music, sound, and silence, after conditioning to enhance sound induced analgesia

Group Type ACTIVE_COMPARATOR

Enhanced Audio

Intervention Type BEHAVIORAL

Audio

Intervention Type BEHAVIORAL

Calibration

Subjects are tested with music, sound, and silence, with no enhanced audio received

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Enhanced Audio

Intervention Type BEHAVIORAL

Audio

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18-50 years old
* Healthy

Exclusion Criteria

* Current diagnoses of psychiatric or neurological disorders or chronic pain
* BDI-II score greater than 13
* current or previous ear/nose/throat or hearing issues
* prior participation in pain studies
* previous advanced music training
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Massachusetts General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Randy L. Gollub

Associate Professor, MD PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Psychiatry, Mass General Hospital

Charlestown, Massachusetts, United States

Site Status

Countries

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United States

References

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Hsieh C, Kong J, Kirsch I, Edwards RR, Jensen KB, Kaptchuk TJ, Gollub RL. Well-loved music robustly relieves pain: a randomized, controlled trial. PLoS One. 2014 Sep 11;9(9):e107390. doi: 10.1371/journal.pone.0107390. eCollection 2014.

Reference Type DERIVED
PMID: 25211164 (View on PubMed)

Other Identifiers

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2012P000969

Identifier Type: -

Identifier Source: org_study_id

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