Effects of Acute Pain on Cognitive Performance in Young Adults
NCT ID: NCT05625776
Last Updated: 2023-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
23 participants
INTERVENTIONAL
2023-03-22
2023-11-16
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Pain Stimulus
Capsaicin combined with heat applied to intact skin
pain delivery with capsaicin and heat
Experimental pain paradigm delivered (capsaicin cream combined with heat) that is short-term and painful but not harmful
Distractor Somatosensory Stimulus
Sensory transcutaneous electrical nerve stimulation (TENS) applied to intact skin
distractor delivery with sensory TENS
Distractor stimulus delivered (sensory TENS electrical stimulation) that is short-term and attention-demanding but not painful
No Stimulus
Nothing applied to skin
No interventions assigned to this group
Interventions
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pain delivery with capsaicin and heat
Experimental pain paradigm delivered (capsaicin cream combined with heat) that is short-term and painful but not harmful
distractor delivery with sensory TENS
Distractor stimulus delivered (sensory TENS electrical stimulation) that is short-term and attention-demanding but not painful
Eligibility Criteria
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Inclusion Criteria
2. Self-identifying as generally medically healthy
3. Able to read, write and speak English
4. Able to provide informed consent
5. Willing to undergo the experimental pain or non-painful electrical stimulation, if selected
Exclusion Criteria
2. Resting BP \< 90/60 or \> 140/95 mmHg
3. Any history or current mental health condition, learning/developmental disability or cognitive impairment, including ADD/ADHD, severe anxiety, severe depression, autism spectrum disorder, insomnia, mild cognitive impairment, etc.
4. Score on the MoCA \<23
5. Score on the GAD-7 ≥ 10
6. Score on the PHQ-2 ≥ 2 and score on the PHQ-9 ≥ 10
7. Any current (within last 3 month) or chronic medical conditions, including any musculoskeletal, cardiovascular, endocrine, pulmonary, metabolic, psychiatric or neurological diagnosis
8. Any implanted electronic medical devices (i.e., cardiac pacemakers, cardiac defibrillators, spinal cord neurostimulators)
9. Any impaired sensation or weakness in either lower extremity or in the area targeted for the stimulus
10. History of serious concussion or head injury, defined as a loss of consciousness for \> 5 minutes and/or requiring medical treatment, or \> 2 concussions over the lifespan
11. Any history of acute or chronic problems with balance, any dizziness, or \> 1 fall in the last 12 months
12. Taking 4 or more medications
13. Currently or regularly using any analgesic medications, over-the-counter remedies, or any other treatment for the purposes of pain relief (i.e., baby aspirin for heart health permitted, etc.)
14. Any current or chronic pain condition during the last year, located anywhere in the body
15. Allergy to capsaicin or hot peppers
16. Any skin lesion, breakage or irritation in the area targeted for the painful stimulus
17. Skin sensitivity to soaps/creams/perfumes or to heat
18. Poor circulation in the area targeted for the painful stimulus
19. Prior participation in a locomotor learning study in this lab within the last 2 years
18 Years
35 Years
ALL
Yes
Sponsors
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National Institute on Aging (NIA)
NIH
University of Delaware
OTHER
Responsible Party
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Susanne M Morton
Associate Professor
Principal Investigators
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Susanne M Morton, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Delaware
Locations
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University of Delaware
Newark, Delaware, United States
Countries
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Other Identifiers
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1786370-1.2
Identifier Type: -
Identifier Source: org_study_id