Effect of the Natural Sweeteners Erythritol and Xylitol on Vascular Function in Obese Volunteers
NCT ID: NCT02821923
Last Updated: 2022-05-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
42 participants
INTERVENTIONAL
2016-11-07
2022-03-10
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
DOUBLE
Study Groups
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Control
no treatment
No interventions assigned to this group
E967-Xylitol
24g xylitol/d
E967-Xylitol
24g xylitol/d
E968-Erythritol
36g erythritol/d
E968-Erythritol
36g erythritol/d
Interventions
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E967-Xylitol
24g xylitol/d
E968-Erythritol
36g erythritol/d
Eligibility Criteria
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Inclusion Criteria
* Aged 18- max. 55 years
* Otherwise healthy.
Exclusion Criteria
* Diabetes mellitus
* Smoking and drug abuse
* Arterial hypertension with antihypertensive treatment
* Dyslipidaemia with statin therapy
* Known chronic hepatic disease (NASH, hepatitis).
* Known renal disease: kidney failure
* Pregnancy
* Chronical diseases of the gastrointestinal tract, history of gastrointestinal surgery with major changes to the gastrointestinal tract
* Substance abuse, alcohol abuse.
* Inability to follow procedures due to psychological disorders, dementia or insufficient knowledge of project language (German).
18 Years
55 Years
ALL
No
Sponsors
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University Hospital, Basel, Switzerland
OTHER
Responsible Party
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Principal Investigators
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Christoph Beglinger, MD
Role: STUDY_CHAIR
St. Claraspital Basel klinische Forschungsabteilung
Locations
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University Hospital
Basel, , Switzerland
Countries
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References
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Bordier V, Teysseire F, Drewe J, Madorin P, Bieri O, Schmidt-Trucksass A, Hanssen H, Beglinger C, Meyer-Gerspach AC, Wolnerhanssen BK. Effects of a 5-week intake of erythritol and xylitol on vascular function, abdominal fat and glucose tolerance in humans with obesity: a pilot trial. BMJ Nutr Prev Health. 2023 Nov 14;6(2):264-272. doi: 10.1136/bmjnph-2023-000764. eCollection 2023.
Other Identifiers
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Poly Vasc
Identifier Type: -
Identifier Source: org_study_id
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