Pre-meal Planning and Expected Satiety

NCT ID: NCT02427152

Last Updated: 2017-05-31

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2015-03-31
• Study Completion Date: 2017-12-31

Brief Summary

Obesity is considered to be caused by an imbalance between energy expenditure and energy intake. A major determinant of our daily energy intake is the size of the meals that we consume. It has been suggested that decisions about portion sizes are often made in advance, before a meal begins. This pre-meal planning is considered to especially depend on the estimated 'expected satiety' and 'expected satiation' of different foods. Further, also factors like weight concern and palatability of the food might have their influence on meal size selection. In general, it is not clear how these factors are integrated during pre-meal planning and which brain networks are involved in these decisions/this process. Thus, the investigators plan to study pre-meal planning in healthy, normal-weight and overweight/obese individuals with functional magnetic resonance imaging under different cognitive instructions including pleasure, expected satiety and self-control in terms of health consequences. The investigators will explore the neural networks involved in pre-meal planning and expect them to be modulated by the before mentioned factors. Further, the investigators plan to explore gender differences and expect that female subjects will select smaller portion sizes especially in the self-control condition as they are often more concerned about their weight/health. Finally, the investigators will explore differences between lean and overweight subjects to elucidate factors that might lead to increased meal sizes in overweight subjects.

Conditions

Adiposity

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Lean

body mass index: 18-25 kg/m²

No interventions assigned to this group

Overweight/Obese

body mass index: \>25 kg/m²

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• body mass index: 18-25 kg/m²; 25-35 kg/m²,
• right-handed,
• age: 18-35 years.

Exclusion Criteria

• functional magnetic resonance imaging contraindications,
• claustrophobia,
• self-reported eating disorders,
• vegan or vegetarian diet, food allergies,
• intake of antidepressants,
• metabolic disorders.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University Hospital Tuebingen

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

University Clinic of Tuebingen, fMEG Center

Tübingen, , Germany

Site Status: RECRUITING

Countries

Germany

Central Contacts

Hege

Role: CONTACT

maike.hege@med.uni-tuebingen.de

Other Identifiers

Satt

Identifier Type: -

Identifier Source: org_study_id