Timing of Meals for Weight Loss

NCT ID: NCT02204735

Last Updated: 2018-04-05

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 8 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-07-31
• Study Completion Date: 2017-11-30

Brief Summary

While eating the majority of energy earlier in the day appears to have a positive effect on weight and cardiometabolic outcomes, it is not clear how eating earlier in the day influences other behaviors that have a circadian rhythm (sleep), other energy balance behaviors important for weight loss (physical activity), and self-reported feelings of appetite control (hunger and fullness). Thus the purpose of this study is to examine the influence of timing of eating on sleep patterns, physical activity, and self-reported feelings of appetite control. It is hypothesized that those who eat the majority of their calories earlier in the day will have greater weight loss than those who eat the majority later in the day.

Detailed Description

Thirty adults will be provided an 8-week standard lifestyle intervention, that includes a 1200-1500 kcal/day, < 30% energy from fat dietary prescription, and a physical activity goal of 200 minutes/week. Participants will be randomized to one of two conditions differing in timing of energy consumed during eating bouts. Both conditions will limit the number of eating bouts/day to three. Participants will be instructed to eat their first eating bout within one hour of awakening and to consume their second and third eating bouts within five or six hours of their previous bout. Participants will be discouraged from eating at least one hour prior to going to sleep. During the intervention, participants will be instructed to self-monitor the time they wake up, the time of the start of each eating bout, and time they go to bed, as well as foods and beverages, and portion sizes, consumed. One condition will consume more energy earlier in the day (MORNING), thus energy intake will be split amongst the three eating bouts with 50% in the first bout, 30% in the second bout, and 20% in the last bout. The second condition will consume more energy later in the day (EVENING), thus energy intake will be split amongst the three eating bouts with 20% in the first bout, 30% in the second bout, and 50% in the last bout.

Conditions

Overweight; Obesity; Weight Loss

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

MORNING

Participants will be instructed to consume 50% of their energy intake in their first eating bout, 30% in their second eating bout, and 20% in their third eating bout. For example, a participant prescribed a 1200 kcal/d diet needs to consume 600 kcal in their first eating bout, 360 kcal in their second bout, and 240 kcal in their third bout. Participants will be provided with sample meal plans meeting this prescription.

Group Type: EXPERIMENTAL

Eat majority of calories in the morning

Intervention Type: BEHAVIORAL

EVENING

Participants will be instructed to consume 20% of their energy intake in their first eating bout, 30% in their second eating bout, and 50% in their third eating bout. For example, a participant prescribed a 1200 kcal/d diet needs to consume 240 kcal in their first eating bout, 360 kcal in their second bout, and 600 kcal in their third bout. Participants will be provided with sample meal plans meeting this prescription.

Group Type: EXPERIMENTAL

Eat the majority of calories in the evening

Intervention Type: BEHAVIORAL

Interventions

Eat majority of calories in the morning

Intervention Type: BEHAVIORAL

Eat the majority of calories in the evening

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• body mass index (BMI) between 27 and 45 kg/m2
• normal self-reported daily (weekday and weekend) wake-up time between 5 am and 8 am
• normal, self-reported weekend wake-up time within two hours of their normal, self-reported weekday wake-up time
• regularly (at least five nights/week) get at least six total hours of self-reported sleep

Exclusion Criteria

• report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q)
• report being unable to walk for 2 blocks (1/4 mile) without stopping
• are currently participating in a weight loss program and/or taking weight loss medication or lost > 5% of body weight during the past 6 months
• are diagnosed with type 1 or 2 diabetes
• have had bariatric surgery or are planning to have bariatric surgery within the next 4 months
• intend to move outside of the metropolitan area within the time frame of the investigation
• are pregnant, lactating, < 6 months post-partum, or plan to become pregnant during the investigation
• are taking mediation to aid in sleep
• are shift workers/alternative shift workers that work outside of 7 am and 7 pm
• have a metal allergy (which would prevent the ability of participant to wear the SenseWear® armband from BodyMedia® used in the proposed study).

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

The University of Tennessee, Knoxville

OTHER

Sponsor Role: lead

Responsible Party

Hollie Raynor

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Hollie Raynor, Ph, RD

Role: PRINCIPAL_INVESTIGATOR

University of Tennessee

Locations

Univeristy of Tennessee--HEAL Lab

Knoxville, Tennessee, United States

Countries

United States

Related Links

http://nutrition.utk.edu/heal-research/

HEAL research information website

Other Identifiers

UTK_9560 B

Identifier Type: -

Identifier Source: org_study_id