Lifestyle, Eating, and Activity Patterns

NCT ID: NCT00944099

Last Updated: 2018-04-05

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2010-01-31
• Study Completion Date: 2011-12-31

Brief Summary

The purpose of this research is to test the effect of manipulating eating frequency on hunger and the reinforcing value of food in 50 overweight/obese adults participating in a 6-month behavioral weight loss intervention.

Detailed Description

Previous observational and experimental research suggests that increased eating frequency is related to lower weight, body mass index (BMI)and body fatness. It is proposed that eating frequently during the day reduces overall energy consumed by preventing the development of excessive hunger. As elevated hunger increases the reinforcing value of food, and greater intake occurs when the reinforcing value of food increases, eating frequently during the day may be a dietary strategy that can aid with reducing energy intake and improving weight loss during a behavioral weight control program. Therefore, the purpose of this proposed research is to test the effect of manipulating eating frequency on hunger and the reinforcing value of food in 50 overweight/obese adults participating in a 6-month behavioral weight loss intervention. Participants will be randomized to 1 of 2 conditions: 1) a condition in which participants will be given an eating frequency prescription to eat every 2 to 3 hours (Grazing); or 2) a condition in which participants will be given an eating frequency prescription of eating 3 meals per day (Three Meals). Both conditions will receive an identical dietary prescription, a low-calorie (1200 to 1500 kcals/d), low-fat (≤ 30% kcals from fat) diet and an identical physical activity goal of 200 minutes of moderate-intense physical activity per week. Additionally, both conditions will receive an identical state-of-the-art, 6-month, behavioral weight loss program.

Conditions

Overweight; Obesity

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Grazing

participants will be given an eating frequency prescription to eat every 2 to 3 hours

Group Type: EXPERIMENTAL

Behavioral weight loss intervention

Intervention Type: BEHAVIORAL

both conditions will receive an identical dietary prescription, low-calorie and less than 30% calories from fat and an identical physical activity goal of 200 minutes of moderate-intense physical activity per week during a 6 month behavioral weight loss program

Three Meals

participants will be given an eating frequency prescription of eating 3 meals per day

Group Type: EXPERIMENTAL

Behavioral weight loss intervention

Intervention Type: BEHAVIORAL

both conditions will receive an identical dietary prescription, low-calorie and less than 30% calories from fat and an identical physical activity goal of 200 minutes of moderate-intense physical activity per week during a 6 month behavioral weight loss program

Interventions

Behavioral weight loss intervention

both conditions will receive an identical dietary prescription, low-calorie and less than 30% calories from fat and an identical physical activity goal of 200 minutes of moderate-intense physical activity per week during a 6 month behavioral weight loss program

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• body mass index (BMI) between 27 and 45 kg/m2

Exclusion Criteria

• report a heart condition, chest pain during periods of activity or rest, or loss of consciousness
• report being unable to walk 1/4 mile without stopping
• report major psychological disease or organic brain syndromes
• report a diagnosis of type I or type II diabetes
• are currently participating in a weight loss program, are taking weight loss medication, have had surgery for weight loss, or have lost > 5% of their body weight in the past 6 months
• are currently participating in a program that manipulates their eating habits
• intent to move outside of the East Tennessee area within the time frame of the intervention
• are pregnant, lactating, less than 6 months post-partum, or plan to become pregnant during the time frame of the intervention
• are unwilling to attend group intervention meetings, assessments, or complete a food diary for the duration of the study

• Minimum Eligible Age: 21 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

American Heart Association

OTHER

Sponsor Role: collaborator

The University of Tennessee, Knoxville

OTHER

Sponsor Role: lead

Responsible Party

Hollie Raynor

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Jessica L Bachman, MS, MPH, RD

Role: PRINCIPAL_INVESTIGATOR

University of Tennessee

Hollie A Raynor, PhD, RD

Role: STUDY_CHAIR

University of Tennessee

Locations

Healthy Eating and Acitivty Laboratory, University of Tennessee

Knoxville, Tennessee, United States

Countries

United States

Other Identifiers

AHA 09PRE2020150

Identifier Type: -

Identifier Source: org_study_id