The Glycemic and Insulinemic Responses Elicited by Meals Containing Whole Grain Rye Bread or White Wheat Bread

NCT ID: NCT02400411

Last Updated: 2015-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-03-31

Brief Summary

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This is a postprandial study with healthy volunteers. The glycemic and insulinemic responses elicited by meals containing either whole grain rye bread or white wheat bread as such or combined with margarine and ham and vegetable soup are compared. Blood glucose concentrations are monitored from finger prick blood samples collected before the meal and at 15, 30, 45, 60, 90 and 120 min. Venous samples for insulin concentrations are taken at time-points 0, 30 and 60 min.

Detailed Description

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Conditions

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Blood Glucose Concentration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Wheat bread

Bread-based meal

Group Type EXPERIMENTAL

Wheat bread

Intervention Type OTHER

Wheat bread with margarine and ham

Bread-based meal

Group Type EXPERIMENTAL

Wheat bread

Intervention Type OTHER

margarine

Intervention Type OTHER

ham

Intervention Type OTHER

Wheat bread with margarine, ham and soup

Bread-based meal

Group Type EXPERIMENTAL

Wheat bread

Intervention Type OTHER

margarine

Intervention Type OTHER

ham

Intervention Type OTHER

soup

Intervention Type OTHER

Rye bread

Bread-based meal

Group Type EXPERIMENTAL

rye bread

Intervention Type OTHER

Rye bread with margarine and ham

Bread-based meal

Group Type EXPERIMENTAL

margarine

Intervention Type OTHER

ham

Intervention Type OTHER

rye bread

Intervention Type OTHER

Rye bread with margarine, ham and soup

Bread-based meal

Group Type EXPERIMENTAL

margarine

Intervention Type OTHER

ham

Intervention Type OTHER

soup

Intervention Type OTHER

rye bread

Intervention Type OTHER

Interventions

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Wheat bread

Intervention Type OTHER

margarine

Intervention Type OTHER

ham

Intervention Type OTHER

soup

Intervention Type OTHER

rye bread

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* female
* BMI 18-27 kg/m2

Exclusion Criteria

* pregnant or breastfeeding
* diabetes, gastrointestinal disease
* regular use of medication
* strict vegetarian or vegan diet
* food allergy
* recent blood donation
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Fazer Group

INDUSTRY

Sponsor Role collaborator

University of Helsinki

OTHER

Sponsor Role lead

Responsible Party

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Mikael Fogelholm

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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HY_RAV_Breadmeal

Identifier Type: -

Identifier Source: org_study_id

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