New Prognostic Kidney Function Markers in Emergency Patients New Markers of Kidney Function in ED Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2015-05-31

Study Completion Date

2016-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

NephroCheck is measuring the concentration of a certain protein combination in the urine of patients. In elevated values there is a probability of renal failure (already proven in intensive care patients). The investigators would like to investigate whether the investigators can predict renal failure in patients receiving contrast enhanced CT's in the emergency department. That would lead to an earlier nephrologist consult in those patients.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Search for New Methods to Detect Acute Renal Failure

NCT00026702

Kidney Disease Kidney Failure Kidney Failure, Chronic +2 more

RECRUITING

Multiparametric MRI in Healthy Volunteers and CKD Patients

NCT05229263

Chronic Kidney Diseases Healthy

ACTIVE_NOT_RECRUITING NA

Evaluation of Novel Biomarkers From Acutely Ill Patients at Risk for Acute Kidney Injury

NCT01209169

Acute Kidney Injury

COMPLETED

Adverse Reactions to MR and CT-examinations (Enhanced and Unenhanced)

NCT01132339

Renal Adverse Events - Contrast Induced Nephropathy (CIN) Non-renal Adverse Events

COMPLETED

Applications of MRI in Kidney Disease

NCT02832505

Chronic Kidney Disease End-stage Kidney Disease

WITHDRAWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The use of contrast agents can - especially in already in impaired renal function - lead to a decline in real function. The contrast enhanced CT is especially in emergency patients an important diagnostic tool for example in the detection of pulmonary embolism or mesenteric ischemia. Creatinine has been used as a marker for real function so far. But the investigators all know that creatinine is not a perfect marker especially as it is influenced by age, sex, weight and muscle mass. Especially in the diagnosis of acute renal failure creatinine does not allow and recent change in the kidney function.

This prospective, unicentric study should therefore investigate two new markers in emergency patients who need an emergency contrast enhanced CT to early predict pending kidney function decline.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Acute Kidney Injury Contrast Media

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

normal creatinine

pts receiving an iv-contrast enhanced CT with normal baseline renal function

No interventions assigned to this group

elevated creatinine

pts receiving an iv-contrast enhanced CT with abnormal baseline renal function

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients in the emergency department who have the indication for contrast enhanced CT and a predicted hospital admission time of 48 hours or longer.