Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
OBSERVATIONAL
2025-10-30
2028-08-30
Brief Summary
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1. To test developed multiple anatomic and functional MRI methods;
2. To evaluate the potentials of these MRI methods in the diagnosis, prognosis, and monitoring of the progression of renal dysfunction.
These purposes will be achieved by performing pilot studies with cohorts of patients.
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Detailed Description
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Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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Non-CKD (Control)
Patients without CKD (eGFR ≥ 60 ml/min/1.73 mm2) (non-CKD controls).
No intervention but only observational.
No intervention but only observational
This study is a cross-sectional and observational MRI study with three cohorts of patients, and no interventions will be applied.
CKD (chronic kidney disease)
Patients with Patients with moderate to severe CKD (eGFR ranging from 26 to 44 ml/min/1.73 mm2).
No intervention but only observational.
No intervention but only observational
This study is a cross-sectional and observational MRI study with three cohorts of patients, and no interventions will be applied.
ESRD (end-stage renal disease)
Patients with advanced CKD (eGFR \< 15 ml/min/1.73 mm2), preparing for or undergoing the standard thrice-weekly HD or standard PD treatment (end-stage renal disease (ESRD) patients).
No intervention but only observational.
No intervention but only observational
This study is a cross-sectional and observational MRI study with three cohorts of patients, and no interventions will be applied.
Interventions
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No intervention but only observational
This study is a cross-sectional and observational MRI study with three cohorts of patients, and no interventions will be applied.
Eligibility Criteria
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Inclusion Criteria
2. Able to complete an approximately 75 to 90 minute cognitive and/or physical tests
3. Capable to consent to studies
Exclusion Criteria
2. Active chemical dependence, such as alcohol, narcotics or other drugs
3. Legally blind or unable to complete cognitive tests due to visual loss or deafness
4. Renal transplant recipient at time of screening or baseline
5. Severe CI unable to complete the Modified Mini-Mental State Examination \[3MSE\]
6. Chronic and acute pulmonary disease
45 Years
ALL
Yes
Sponsors
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University of Minnesota
OTHER
Responsible Party
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Principal Investigators
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Xiufeng Li
Role: PRINCIPAL_INVESTIGATOR
University of Minnesota
Locations
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University of Minnesota Medical Center
Minneapolis, Minnesota, United States
Countries
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Other Identifiers
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1603M85321
Identifier Type: -
Identifier Source: org_study_id
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