Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
25 participants
OBSERVATIONAL
2013-06-30
2014-03-31
Brief Summary
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Detailed Description
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Methods:Measure the lung strain in the tidal volume of 6mL/kg,8mL/kg,10mL/kg and 12mL/kg in each ARDS patient.
Hypothesis:With the increase of the tidal volume,the lung strain develops.In the patient with larger lung compliance,the strain of the group of conventional tidal volume is less than 0.27 and there is no obvious difference between the group of small tidal volume.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
2. Needing Invasive ventilation
3. Fit the definition of ARDS in 2012 "Berlin Definition"
4. Sign the paper of informed consent
Exclusion Criteria
2. the COPD patients
3. less than 24h of mechanical ventilation
4. more than 5 days of mechanical ventilation
5. FiO2\>80%
6. presence of air leaks
7. organ dysfunction and hemodynamic instability
8. including in other research
18 Years
85 Years
ALL
No
Sponsors
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Zhongda Hospital
OTHER
Responsible Party
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Xiaohua Qiu
physician
Locations
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Affiliated Zhongda Hospital of Southeast University
Nanjing, Jiangsu, China
Countries
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Central Contacts
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Facility Contacts
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References
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Xie J, Jin F, Pan C, Liu S, Liu L, Xu J, Yang Y, Qiu H. The effects of low tidal ventilation on lung strain correlate with respiratory system compliance. Crit Care. 2017 Feb 3;21(1):23. doi: 10.1186/s13054-017-1600-x.
Other Identifiers
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20130519
Identifier Type: -
Identifier Source: org_study_id
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