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Optimization of PEEP for Alveolar Recruitment in ARDS

NCT ID: NCT01949272

Last Updated: 2016-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

22 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-09-30

Study Completion Date

2016-05-31

Brief Summary

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Actual setting of PEEP in ARDS is based on tables linked to FiO2, or respiratory system plateau pressure (e.g EXPRESS Study) or set regarding esophageal pressure mesurement and transpulmonary pressure calculation. Opera study should confirm if a setting approach based on esophageal pressure is helpfull for any ARDS patient in ICU without deleterious side-effect.

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Detailed Description

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Conditions

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ARDS

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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ARDS

ARDS patients achieving stades II and III of Berlin 2011 Classification

esophageal pressure mesurement

Intervention Type DEVICE

"EXPRESS study" ventilatory setting the optimization of PEEP with esophageal pressure mesurement

Interventions

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esophageal pressure mesurement

"EXPRESS study" ventilatory setting the optimization of PEEP with esophageal pressure mesurement

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* ARDS Stades 2 and 3 with invasive ventilation (EXPRESS settings) within 3 to 12 hours

Exclusion Criteria

* less 18 years, pregnancy, intracardiac shunt, esophageal catheter cons-indicated
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Melun Hospital Intensive Care Unit

UNKNOWN

Sponsor Role collaborator

Hopital of Melun

OTHER

Sponsor Role lead

Responsible Party

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Sebastien Jochmans, MD

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mehran Monchi, MD

Role: STUDY_DIRECTOR

Melun Hospital ICU

Locations

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Melun Hospital ICU

Melun, , France

Site Status

Countries

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France

Other Identifiers

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OPERA

Identifier Type: -

Identifier Source: org_study_id

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