Prevalence of Toxoplasma Gondii and Toxocara Canis Among Patients With Uveitis

NCT ID: NCT01837056

Last Updated: 2013-04-22

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 98 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2011-01-31
• Study Completion Date: 2012-02-29

Brief Summary

Investigate the prevalence of Toxoplasma gondii and Toxocara canis in Uveitis

• serum antibody to T. gondii and T. canis
• PCR with peripheral blood for T. gondii and T. canis
• PCR with aqueous humor for T. gondii and T. canis
• Clinical manifestation of patient with uveitis

Detailed Description

Consecutive patients with uveitis are enrolled in Nune Eye Hospital.

Serum ELISA

• IgM,IgG antibody to Toxoplasma gondii
• IgG antibody to Toxocara canis

PCR

• PCR with serum and aqueous humor to Toxoplasma gondii
• PCR with serum and aqueous humor to Toxocara canis Clinical characteristics
• visual acuity
• intraocular pressure (IOP)
• location and degree of inflammation
• other fundus findings were recorded

questionnaire

• environment, occupation
• pet ownership, exposure to animal
• history of eating raw liver of animal, raw beef or any other raw flesh of animal.

Conditions

Uveitis

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• patients with uveitis

Exclusion Criteria

• Patients with history of major ophthalmic surgery within 6 months
• antiviral, antifungal or antiparasitic therapy within 6 months

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National Institute of Health, Korea

OTHER_GOV

Sponsor Role: lead

Responsible Party

Lim, Su Jin

The retina staff

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Su Jin Lim, MD

Role: PRINCIPAL_INVESTIGATOR

Nune Eye Hospital

Other Identifiers

Nuneuveitis

Identifier Type: -

Identifier Source: org_study_id