Saccadic Eye Movements Are Impaired In Glaucoma

NCT ID: NCT01254058

Last Updated: 2019-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-07-31

Study Completion Date

2020-04-30

Brief Summary

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The purpose of this study is to determine whether rapid eye movements called saccades are impaired in glaucoma, a neurodegenerative disease of visual pathways.

Detailed Description

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Eye movements that quickly scan a visual scene are critical to a number of daily activities including driving. It is not known whether rapid eye movement called saccades, are altered in glaucoma.

Conditions

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Glaucoma, Open-Angle

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Glaucoma Group

No interventions assigned to this group

Age-Matched Controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Ages from 40-80 years. Primary open angle glaucoma is defined by characteristic glaucomatous optic nerve head findings and the presence of corresponding visual field deficits in one or both eyes. All control subjects will be age-matched, with no ocular medical or surgical history, and a completely normal eye examination. Age-matched controls will be recruited from local hospital personnel and accompanying relatives.

Exclusion Criteria

* Any patient with a history of other eye disease, neurological disease or neurodegenerative disorder, or history of incisional ocular surgery within the previous month will be excluded.
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Unity Health Toronto

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Neeru Gupta, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Unity Health Toronto

Locations

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St. Michael's Hospital

Toronto, Ontario, Canada

Site Status

Countries

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Canada

References

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Gupta N, Krishnadev N, Hamstra SJ, Yucel YH. Depth perception deficits in glaucoma suspects. Br J Ophthalmol. 2006 Aug;90(8):979-81. doi: 10.1136/bjo.2006.091025. Epub 2006 May 3.

Reference Type BACKGROUND
PMID: 16672326 (View on PubMed)

Kanjee R, Yucel YH, Steinbach MJ, Gonzalez EG, Gupta N. Delayed saccadic eye movements in glaucoma. Eye Brain. 2012 Nov 26;4:63-68. doi: 10.2147/EB.S38467. eCollection 2012.

Reference Type RESULT
PMID: 28539782 (View on PubMed)

Other Identifiers

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REB 06-056

Identifier Type: -

Identifier Source: org_study_id

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