Central Corneal Thickness in Glaucoma

NCT ID: NCT01023997

Last Updated: 2014-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-31

Study Completion Date

2013-01-31

Brief Summary

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The purpose of this study is to compare the central corneal thickness measurement in patients with exfoliation syndrome, exfoliative glaucoma, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma.

Detailed Description

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To compare the central corneal thickness measurement in patients with exfoliation, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma. Prospective study in progress. Randomly selected patients undergo a comprehensive ophthalmic exam which includes 2 separate pachymetry measurements in 2 different examinations at the same time of the day (10:00 am) with 3 different pachymeters. The values obtained are correlated with a number of other glaucoma parameters. A thinner cornea may represent a specific attribute and an additional risk factor for patients with exfoliation. Evaluation of corneal thickness is an important exam in the management of patients with exfoliation.

Conditions

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Exfoliation Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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primary open-angle glaucoma

No interventions assigned to this group

ocular hypertension patients

No interventions assigned to this group

normal controls

No interventions assigned to this group

Exfoliation patients

patients with exfoliation syndrome or exfoliative glaucoma

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Exfoliation material on pupil
* Intraocular pressure below 21 mm Hg without glaucomatous damage
* Intraocular pressure above 21 mm Hg without glaucomatous damage
* Raised intraocular pressure with glaucomatous damage

Exclusion Criteria

* Corneal disorders
* History of trauma
* Evidence of corneal abnormality that may influence IOP
* Contact lens use
* Corneal surgery
Minimum Eligible Age

25 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Aristotle University Of Thessaloniki

OTHER

Sponsor Role lead

Responsible Party

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AGP Konstas

Professor in Ophthalmology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kostantinos Kaltsos, MD, PhD

Role: STUDY_DIRECTOR

1st University Dept of Ophthalmology

Locations

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Glaucoma Unit, 1st University Department of Ophthalmology

Thessaloniki, , Greece

Site Status

Countries

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Greece

Other Identifiers

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A3502

Identifier Type: -

Identifier Source: org_study_id

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