Venous Function in Cardiovascular Disease Patients

NCT ID: NCT01474408

Last Updated: 2017-02-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-11-30

Study Completion Date

2012-11-30

Brief Summary

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The primary aim is to determine the acute effect of two different training interventions on venous plasticity in patients with myocardial infarction (MI), revascularization or coronary artery graft surgery compared to age-matched healthy subjects.

Detailed Description

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Compare the effect of 4 x 4 minutes at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate and moderate continuous exercise at 70 % of peak heart rate on venous function.

Conditions

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Myocardial Infarction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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interval training

4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate

Group Type EXPERIMENTAL

interval training day 1

Intervention Type BEHAVIORAL

Moderate exercise day 2

Intervention Type BEHAVIORAL

Control day 3

Intervention Type BEHAVIORAL

moderate exercise

moderate continuous exercise at 70 % of peak heart rate on venous function.

Group Type ACTIVE_COMPARATOR

interval training day 1

Intervention Type BEHAVIORAL

Moderate exercise day 2

Intervention Type BEHAVIORAL

Control day 3

Intervention Type BEHAVIORAL

control

routine measurements, no exercise

Group Type OTHER

interval training day 1

Intervention Type BEHAVIORAL

Moderate exercise day 2

Intervention Type BEHAVIORAL

Control day 3

Intervention Type BEHAVIORAL

Interventions

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interval training day 1

Intervention Type BEHAVIORAL

Moderate exercise day 2

Intervention Type BEHAVIORAL

Control day 3

Intervention Type BEHAVIORAL

Other Intervention Names

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aerobic interval training

Eligibility Criteria

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Inclusion Criteria

* myocardial infraction (MI)
* revascularization (PCI)
* coronary artery bypass graft surgery (CABG)

Exclusion Criteria

* unstable angina pectoris
* uncontrolled hypertension
* orthopedic and/or neurological limitations
* participation in other studies
* MI (closer than 4 weeks)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ulrik Wisløff, prof

Role: STUDY_DIRECTOR

Norwegian University of Science and Technology

Locations

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Institutt for Sirkulasjon og Bildetechnikk, NTNU

Trondheim, , Norway

Site Status

Countries

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Norway

References

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Leinan IM, Aamot IL, Stoylen A, Karlsen T, Wisloff U. Upper arm venous compliance and fitness in stable coronary artery disease patients and healthy controls. Clin Physiol Funct Imaging. 2017 Sep;37(5):498-506. doi: 10.1111/cpf.12324. Epub 2015 Dec 15.

Reference Type RESULT
PMID: 26667796 (View on PubMed)

Other Identifiers

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2011/760

Identifier Type: -

Identifier Source: org_study_id

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