Training at Different Intensities in Coronary Artery Disease -Effects on Myocardial Function

NCT ID: NCT00201591

Last Updated: 2011-08-26

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 17 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2002-08-31
• Study Completion Date: 2004-01-31

Brief Summary

The study investigated if aerobic endurance exercise of different intensity has different impact on the physical capacity and myocardial function in patients with coronary artery disease. Patients with stable CAD trained for 10 weeks, and oxygen consumption and myocardial function were measured before and after this period. Patients were randomly assigned to each exercise group.

Detailed Description

Peak oxygen consumption was measured by gas-analysis. Myocardial function was measured by echocardiography. Exercise was performed on treadmills under close supervision of an exercise physiologist. Patients had to complete over 70% of sessions to be included in analysis. Three sessions were scheduled every week. Heart rate (HR) was about 85 % of max HR in the high intensity group, and about 65 % in the moderate intensity group.

Conditions

Coronary Artery Disease

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Interventions

Exercise training for 10 weeks

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• stable coronary artery disease
• over 4 months since cardiovascular event

Exclusion Criteria

• heart failure
• inability to exercise

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

St. Olavs Hospital

OTHER

Sponsor Role: collaborator

Norwegian University of Science and Technology

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Stig A Slørdahl, Prof

Role: STUDY_CHAIR

Norwegian University of Science and Technology

Locations

Dept. of Circulation and Medical Imaging, NTNU

Trondheim, , Norway

Countries

Norway

References

Amundsen BH, Rognmo O, Hatlen-Rebhan G, Slordahl SA. High-intensity aerobic exercise improves diastolic function in coronary artery disease. Scand Cardiovasc J. 2008 Apr;42(2):110-7. doi: 10.1080/14017430701744477.

Reference Type: RESULT

PMID: 18365893 (View on PubMed)

Other Identifiers

Trehab I NTNU

Identifier Type: -

Identifier Source: org_study_id