High-intensity Exercise Training in Patients With Post-infarction Heart Failure
NCT ID: NCT00218933
Last Updated: 2017-02-09
Study Results
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Basic Information
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COMPLETED
NA
27 participants
INTERVENTIONAL
2001-10-31
2005-09-30
Brief Summary
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Methods: Patients with post-infarction heart failure (45-87 yrs, 22-males, 5-females, all received b-blockers and ACE-inhibitors, EF 29%, peak oxygen uptake 13 ml/kg/min) were randomized to 12-weeks, 2-3 times per week, of either moderate exercise-intensity (70% of peak heart rate), high-intensity interval-training (95% of peak heart rate) or to a control group that received advise from their regular doctors. Patients in the two exercise-groups covered similar distance on the treadmill at each exercise-session so that only exercise-intensity differed; i.e. the duration of exercise was longer in the moderate-intensity group. Ultrasound was used to assess LV-dimension and function (including Tissue Doppler Imaging, TDI) and endothelial function in the brachial-artery.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
SINGLE
Study Groups
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moderate exercise training
Moderate intensity exercise training
12-weeks, 2-3 times per week moderate exercise-intensity (70% of peak heart rate)
high intensity exercise training
High intensity exercise training
12-weeks, 2-3 times per week high-intensity interval-training (95% of peak heart rate)
controls
No interventions assigned to this group
Interventions
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Moderate intensity exercise training
12-weeks, 2-3 times per week moderate exercise-intensity (70% of peak heart rate)
High intensity exercise training
12-weeks, 2-3 times per week high-intensity interval-training (95% of peak heart rate)
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
30 Years
ALL
No
Sponsors
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Norwegian University of Science and Technology
OTHER
Responsible Party
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Principal Investigators
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Ulrik Wisloff, Ph.D
Role: PRINCIPAL_INVESTIGATOR
Norwegian University of Science and Technology
Locations
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Norwegian University of Science and Technology
Trondheim, , Norway
Countries
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References
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Wisloff U, Stoylen A, Loennechen JP, Bruvold M, Rognmo O, Haram PM, Tjonna AE, Helgerud J, Slordahl SA, Lee SJ, Videm V, Bye A, Smith GL, Najjar SM, Ellingsen O, Skjaerpe T. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation. 2007 Jun 19;115(24):3086-94. doi: 10.1161/CIRCULATIONAHA.106.675041. Epub 2007 Jun 4.
Other Identifiers
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HFEX-1
Identifier Type: -
Identifier Source: org_study_id
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