Exercise Effect on Aerobic Capacity and QOL in Heart Failure
NCT ID: NCT00013221
Last Updated: 2015-04-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
84 participants
INTERVENTIONAL
2000-03-31
Brief Summary
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Detailed Description
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Chronic heart failure (HF) is a syndrome of impaired ventricular function resulting in clinical symptoms of fatigue, dyspnea, and decreased exercise capacity. These symptoms lead to a cyclical pattern of an increasing sedentary lifestyle with accompanying deconditioning and deterioration of muscle function. Until recently, the prescription for individuals with HF was rest and minimization of physical exertion.
Objectives:
The primary objectives of this randomized clinical trial were to determine whether subjects, with moderate to severe chronic HF, who completed a 12-week individualized program of cardiopulmonary training (exercise group) would have significantly greater (i) quality of life, measured by the Rand Short Form-36, and (ii) aerobic fitness, measured by oxygen uptake during symptom limited maximal metabolic treadmill testing, than subjects who met weekly with an investigator and received vital sign measurements (non-exercise group).
Methods:
A randomized controlled clinical trial was utilized. Individuals who met the inclusion criteria were randomly assigned to either an exercise or control group. Individuals in the exercise group received 36 weeks of exercise training (primary outcome variables were measured at 12 weeks). Participants in the control group received weekly visits with a nurse for 12 weeks.
Status:
Ongoing data analysis for publication. Final report submitted.
Conditions
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
NONE
Study Groups
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Arm 1
Exercise
Interventions
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Exercise
Eligibility Criteria
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Inclusion Criteria
18 Years
ALL
No
Sponsors
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US Department of Veterans Affairs
FED
Responsible Party
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Principal Investigators
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Eileen G. Collins, PhD RN
Role: PRINCIPAL_INVESTIGATOR
Edward Hines Jr. VA Hospital, Hines, IL
Walter Edwin Langbein, PhD
Role: PRINCIPAL_INVESTIGATOR
Edward Hines Jr. VA Hospital, Hines, IL
Locations
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Edward Hines Jr. VA Hospital, Hines, IL
Hines, Illinois, United States
Countries
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References
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Collins E, Langbein WE, Dilan-Koetje J, Bammert C, Hanson K, Reda D, Edwards L. Effects of exercise training on aerobic capacity and quality of life in individuals with heart failure. Heart Lung. 2004 May-Jun;33(3):154-61. doi: 10.1016/j.hrtlng.2003.12.009.
Other Identifiers
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NRI 95-213
Identifier Type: -
Identifier Source: org_study_id
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