Exercise Intervention in Patients With Heart Failure With Preserved and Reduced Ejection Fraction
NCT ID: NCT05255172
Last Updated: 2025-06-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
NA
120 participants
INTERVENTIONAL
2022-06-01
2027-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Supervised exercise
The exercise intervention will include 2 supervised sessions of ergometer cycling with a warm up period of 10 minutes and 20 minutes of cycling at the aerobic intensity below the anaerobic threshold as determined from baseline results. Patients in the exercise arm will have 1 unsupervised exercise session where the participants walk or bicycle for 30 minutes at an intensity experienced as somewhat hard (Borg 13) according to the Borg Rating of Perceived Exertion Scale.
Supervised Exercise
12 weeks of supervised aerobic exercise individually adapted to exercise capacity according to a VO2 peak test
Standard of Care
The control group will receive advise to continue to live as usual. After 4 and 8 weeks, participants in the control group will be contacted by telephone for inquiry of general wellbeing. No other interventions will be performed in the control group.
No interventions assigned to this group
Interventions
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Supervised Exercise
12 weeks of supervised aerobic exercise individually adapted to exercise capacity according to a VO2 peak test
Eligibility Criteria
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Inclusion Criteria
2. Age ≥50 years
3. Stable chronic heart failure (no hospitalizations within past month, no new medications past month)
4. Able to understand and follow exercise prescription
5. Currently physically inactive (less than 150 minutes/week moderate intensity exercise)
Exclusion Criteria
2. Devices or implants not compatible with magnetic resonance imaging or exercise testing
3. Any orthopedic or medical condition affecting participation in testing and training
4. Signs of acute ischemia during baseline cardiopulmonary exercise testing
5. Participation in other clinical trials that may affect results
6. Moderate or severe valvular disease
7. Atrial fibrillation
8. Moderate or severe chronic obstructive pulmonary disease
9. NYHA class IV
50 Years
90 Years
ALL
No
Sponsors
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Region Skane
OTHER
Responsible Party
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Locations
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Skåne University Hospital Lund
Lund, , Sweden
Countries
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Other Identifiers
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2021-05044
Identifier Type: -
Identifier Source: org_study_id
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