Heart Failure and Regional Specific Exercise Training Stimulus

NCT ID: NCT02077426

Last Updated: 2014-09-17

Basic Information

• Recruitment Status: WITHDRAWN
• Clinical Phase: NA
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-06-30

Brief Summary

The aim of this study is to determine whether heart failure patients can tolerate a four-weeks of a new exercise training regimen that targets peripheral tissues (Regional Specific Training Stimulus-RSTS) and has been show to produce significant benefits in aerobic capacity and strength in healthy subjects aged 70+years who were at risk for losing functional independence.

Conditions

Heart Failure; Sedentary

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Regional Specific Training (RSTS)

The RSTS protocol was designed to focus on specific peripheral muscle groups without imposing a significant cardiorespiratory strain. Each exercise involved contractions with moderate load but with an extended duration of up to six minutes. Eight specific exercises were performed to target all major muscle groups and enable the routine to be completed within 60 minutes including warm-up, rest periods and stretching between exercises, and cool down exercises

Group Type: EXPERIMENTAL

Regional Specific Training (RSTS)

Intervention Type: OTHER

The RSTS protocol was designed to focus on specific peripheral muscle groups without imposing a significant cardiorespiratory strain. Each exercise involved contractions with moderate load but with an extended duration of up to six minutes. Eight specific exercises were performed to target all major muscle groups and enable the routine to be completed within 60 minutes including warm-up, rest periods and stretching between exercises, and cool down exercises.

Interventions

Regional Specific Training (RSTS)

The RSTS protocol was designed to focus on specific peripheral muscle groups without imposing a significant cardiorespiratory strain. Each exercise involved contractions with moderate load but with an extended duration of up to six minutes. Eight specific exercises were performed to target all major muscle groups and enable the routine to be completed within 60 minutes including warm-up, rest periods and stretching between exercises, and cool down exercises.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Men and women between the ages of 55 and 90
• Diagnosed with heart failure (NYHA class II-III)
• Receiving optimal medical therapy
• Sedentary (≤ 30 min/wk structured physical activity)
• Peak VO2 between 10 and 30 mL/kg/min.

Exclusion Criteria

• Oxygen dependent
• Recent medications changes (within 3 months)
• Fixed-rate pacemakers
• Uncontrolled hypertension
• Type I diabetes
• Organ transplant
• Bariatric surgery
• Renal failure (stage 4 or 5)

• Minimum Eligible Age: 55 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Duke University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Jason D Allen, PhD

Role: PRINCIPAL_INVESTIGATOR

Duke University

Locations

Duke Center for Living; Wallace Clinic

Durham, North Carolina, United States

Countries

United States

Other Identifiers

Pro00051711

Identifier Type: -

Identifier Source: org_study_id