Imminently Effect of Interval Training With High Intensity (HIT) After Heart Transplantation
NCT ID: NCT02602834
Last Updated: 2016-11-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
19 participants
INTERVENTIONAL
2015-05-31
2015-11-30
Brief Summary
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Detailed Description
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The study is designed to be a cross-over study. And randomisation will decide which training they will have som training session 1 and training session 2; Interval or continuous training.
Before starting the two training sessions they will measure oxygen uptake and baseline blood samples.
During each exercise session the patients will take blood samples during and after exercise.
After first study admission the patients will have a wash out period for 1 week until first training session, and another week until the last session.
Conditions
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Keywords
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
NONE
Study Groups
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HTx
Heart transplant recipients n=15
interval training
4 intervals with high intensity on treadmill, and approximately 3 minutes rest between intervals.
moderate exercise
30 minutes (moderate intensity) aerobic exercise on treadmill without rest.
Control
Healthy controls n=5
interval training
4 intervals with high intensity on treadmill, and approximately 3 minutes rest between intervals.
moderate exercise
30 minutes (moderate intensity) aerobic exercise on treadmill without rest.
Interventions
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interval training
4 intervals with high intensity on treadmill, and approximately 3 minutes rest between intervals.
moderate exercise
30 minutes (moderate intensity) aerobic exercise on treadmill without rest.
Eligibility Criteria
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Inclusion Criteria
* Lives in Oslo or near Oslo
* Stable health condition
* Optimal medical treatment/ medication
* No limiting physical handicap
* Written consent
Inclusion healthy control:
* No verified heart disease
* Willing to preform the study
* Over 18 years
* Written consent
Exclusion Criteria
* Lives far from Oslo
* Unstable health condition
* Not optimal medical treatment and/ or medication
* Limiting physical handicap
* Under 18 years
* Not written consent
18 Years
ALL
Yes
Sponsors
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Norwegian Health Association
OTHER
Oslo University Hospital
OTHER
Responsible Party
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Marianne Yardley
MD, PhD candidate
Principal Investigators
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Lars LG Gullestad, professor
Role: STUDY_DIRECTOR
OUS-Oslo university hospital rikshospitalet, cardiology department
Locations
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OUS- Rikshospitalet
Oslo, Oslo County, Norway
Countries
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References
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Yardley M, Ueland T, Aukrust P, Michelsen A, Bjorkelund E, Gullestad L, Nytroen K. Immediate response in markers of inflammation and angiogenesis during exercise: a randomised cross-over study in heart transplant recipients. Open Heart. 2017 Nov 28;4(2):e000635. doi: 10.1136/openhrt-2017-000635. eCollection 2017.
Other Identifiers
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2015/97/REK sør-øst A
Identifier Type: -
Identifier Source: org_study_id