Exercise-training Before Coronary Artery Bypass Graft (CABG)

NCT ID: NCT00218985

Last Updated: 2018-02-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-01-31

Study Completion Date

2016-12-31

Brief Summary

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The aim is to evaluate the effect of exercise training upon endothelial function in the mammary artery of patients who are scheduled for CABG, as well as study the functional properties of single cells isolated from a small biopsy of the left ventricle obtained during surgery.

Detailed Description

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Conditions

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Angina Coronary Artery Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Investigators

Study Groups

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exercise training

Group Type EXPERIMENTAL

Exercise training

Intervention Type BEHAVIORAL

Intensity controlled exercise training before the scheduled bypass surgery

physician's advice

patients follow their physician's advice in regard to physical activity.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Exercise training

Intensity controlled exercise training before the scheduled bypass surgery

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Scheduled for CABG both with and without heart failure

Exclusion Criteria

* Unstable angina
* Unable to walk on a treadmill (except those with heart failure who only will serve as a reference group)
* Participation in another study
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ulrik Wisloff, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Norwegian University of Science and Technology

Locations

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Norwegian University of Science and Technology

Trondheim, , Norway

Site Status

Countries

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Norway

References

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Smenes BT, Baekkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Hoydal M, Wisloff U, Rognmo O, Wahba A. Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg. 2018 Jul 1;27(1):95-101. doi: 10.1093/icvts/ivx439.

Reference Type RESULT
PMID: 29447379 (View on PubMed)

Other Identifiers

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TRIM 158-04

Identifier Type: -

Identifier Source: org_study_id

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