Periodization of Exercise Training in Patients With Coronary Heart Disease.

NCT ID: NCT03443193

Last Updated: 2022-09-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-12-16

Study Completion Date

2021-12-31

Brief Summary

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The research project includes two components that assess exercise physiology parameters, cerebrovascular reserve, cognitive functions and cardiac function in coronary heart disease patients at rest, during an acute exercise, and after two different periodized training programs.

Detailed Description

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Conditions

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Coronary Heart Disease Healthy Control

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Linear training

Linear training consists to a progressive improvement of the training load during the 3 month-program.

Group Type EXPERIMENTAL

Exercise training

Intervention Type OTHER

Patients will undergo three weekly exercise training sessions with periodized high-intensity interval training and resistance training for a period of 12 weeks.

Non-linear training

Non-linear training consists to an undulating progressive improvement of the training load during the 3 month-program.

Group Type EXPERIMENTAL

Exercise training

Intervention Type OTHER

Patients will undergo three weekly exercise training sessions with periodized high-intensity interval training and resistance training for a period of 12 weeks.

Interventions

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Exercise training

Patients will undergo three weekly exercise training sessions with periodized high-intensity interval training and resistance training for a period of 12 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Major
* Adequate physical and mental capacities
* Autonomy in daily activities
* Documented coronary artery disease
* Stable or recent coronary artery disease

Exclusion Criteria

* Inability to complete the consent form
* Acute coronary syndrome \< 3 months
* Heart failure
* Ejection fraction of the left ventricle \<40%
* Coronary artery disease non revascularisable including left main coronary stenosis
* Waiting for a bridging of the coronary artery
* Chronic atrial fibrillation
* Malignant arrhythmias during exercise
* Restriction to non cardiopulmonary exercise
* Severe intolerance to exercise
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Montreal Heart Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Cardiovascular prevention and rehabilitation center

Montreal, Quebec, Canada

Site Status

Countries

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Canada

References

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Boidin M, David LP, Trachsel LD, Gayda M, Tremblay J, Lalonge J, Juneau M, Nigam A, Henri C. Impact of 2 different aerobic periodization training protocols on left ventricular function in patients with stable coronary artery disease: an exploratory study. Appl Physiol Nutr Metab. 2021 May;46(5):436-442. doi: 10.1139/apnm-2020-0423. Epub 2020 Oct 27.

Reference Type DERIVED
PMID: 33108743 (View on PubMed)

Trachsel LD, Boidin M, Henri C, Fortier A, Lalonge J, Juneau M, Nigam A, Gayda M. Women and men with coronary heart disease respond similarly to different aerobic exercise training modalities: a pooled analysis of prospective randomized trials. Appl Physiol Nutr Metab. 2021 May;46(5):417-425. doi: 10.1139/apnm-2020-0650. Epub 2020 Oct 23.

Reference Type DERIVED
PMID: 33096006 (View on PubMed)

Other Identifiers

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MontrealHI 2015-1895

Identifier Type: -

Identifier Source: org_study_id

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