Effect of Aerobic or Resistance Exercise on the Endothelial Response in Post-acute Myocardial Infarction Patients Submitted to Angioplasty

NCT ID: NCT04000893

Last Updated: 2019-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-01

Study Completion Date

2019-06-25

Brief Summary

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Cardiac Rehabilitation, as art and acting science multiprofessional, is based on the training with exercises that provides the post-infarct patients to satisfactorily re-establish the patient's clinical condition and that improve the functional capacity of these individuals.

Evidence shows that aerobic exercise training provides improvements in the endothelial function of this population. However, we do not yet have strong evidence of other modalities of exercise in these parameters in post-infarction patients treated with angioplasty.

Detailed Description

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Conditions

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Cardiac Rehabilitation Aerobic Exercise Resistance Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Resistance exercise session

Acute isometric session, about 20 minutes.

Group Type EXPERIMENTAL

Resistance exercise session

Intervention Type OTHER

Acute isometric exercise session performed with handgrip Jamar about 20 minutes monitored.

Aerobic exercise session

Acute aerobic session, about 20 minutes.

Group Type ACTIVE_COMPARATOR

Resistance exercise session

Intervention Type OTHER

Acute isometric exercise session performed with handgrip Jamar about 20 minutes monitored.

Interventions

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Resistance exercise session

Acute isometric exercise session performed with handgrip Jamar about 20 minutes monitored.

Intervention Type OTHER

Other Intervention Names

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Aerobic exercise session

Eligibility Criteria

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Inclusion Criteria

* Post-acute myocardial infarction patients
* Ergometric test 30 days after the infarction
* Ejection fraction\> 40% (Simpson's method)
* Regular use of optimized drugs

Exclusion Criteria

* Unable to perform the randomized exercise
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Instituto de Cardiologia do Rio Grande do Sul

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alexandre Lehnen, PhD

Role: PRINCIPAL_INVESTIGATOR

Instituto de Cardiologia do Rio Grande do Sul

Locations

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Alexandre Lehnen

Porto Alegre, Rio Grande do Sul, Brazil

Site Status

Countries

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Brazil

References

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Kollet DP, Marenco AB, Belle NL, Barbosa E, Boll L, Eibel B, Waclawovsky G, Lehnen AM. Aerobic exercise, but not isometric handgrip exercise, improves endothelial function and arterial stiffness in patients with myocardial infarction undergoing coronary intervention: a randomized pilot study. BMC Cardiovasc Disord. 2021 Feb 17;21(1):101. doi: 10.1186/s12872-021-01849-2.

Reference Type DERIVED
PMID: 33596832 (View on PubMed)

Other Identifiers

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AMI and exercise

Identifier Type: -

Identifier Source: org_study_id

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