Aerobic Interval Training in Patients With Atrial Fibrillation

NCT ID: NCT01325675

Last Updated: 2016-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-04-30

Study Completion Date

2014-02-28

Brief Summary

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The purpose of this study is to determine the effect of aerobic interval training in patients with paroxysmal or persistent atrial fibrillation, especially to see if the burden of atrial fibrillation and symptoms are reduced.

Detailed Description

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Long term endurance sport practice is associated with a higher incidence of atrial fibrillation. Moderate/light physical activity seems to be associated with a lower incidence. The underlying mechanisms are uncertain. In order to examine the effect of training in this population, the investigators will perform a randomised controlled study with aerobic interval training in patients with paroxysmal/persistent atrial fibrillation.

Conditions

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Atrial Fibrillation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Interval training

Interval training

Group Type EXPERIMENTAL

Interval training

Intervention Type BEHAVIORAL

Aerobic interval training will be performed with 4 times of 4 minutes intervals at an intensity of 90-95% of maximum heart rate and active pauses of 3 minutes between intervals. 3 times a week for 12 weeks.

Control

Live as usual

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Interval training

Aerobic interval training will be performed with 4 times of 4 minutes intervals at an intensity of 90-95% of maximum heart rate and active pauses of 3 minutes between intervals. 3 times a week for 12 weeks.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients with paroxysmal or persistent atrial fibrillation, that are able to perform aerobic interval training.

Exclusion Criteria

* Performing high intensity training (pulse \>90% of max) for more than 2 times a week.
* Moderate intensity training more than 30 min, more than 3 times a week
* Previous open heart surgery
* EF \<40%
* Significant aorta stenosis
* Mitral insufficiency, \>gr. 2
* Pacemaker
* Earlier coronary intervention and not complete revascularization
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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St. Olavs Hospital

OTHER

Sponsor Role collaborator

SINTEF Health Research

OTHER

Sponsor Role collaborator

Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jan Paal Loennechen, PhD

Role: STUDY_CHAIR

St. Olavs Hospital

Ulrik Wisløff, PhD

Role: STUDY_CHAIR

Norwegian University of Science and Technology

Locations

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Norwegian University of Science and Technology

Trondheim, Trondheim, Norway

Site Status

Countries

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Norway

References

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Malmo V, Nes BM, Amundsen BH, Tjonna AE, Stoylen A, Rossvoll O, Wisloff U, Loennechen JP. Aerobic Interval Training Reduces the Burden of Atrial Fibrillation in the Short Term: A Randomized Trial. Circulation. 2016 Feb 2;133(5):466-73. doi: 10.1161/CIRCULATIONAHA.115.018220. Epub 2016 Jan 5.

Reference Type RESULT
PMID: 26733609 (View on PubMed)

Other Identifiers

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2010/3345-1(REK)

Identifier Type: -

Identifier Source: org_study_id

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