Comparison of 1 vs 3 Sets of Resistance Training on Muscular Hypertrophy

NCT ID: NCT01107691

Last Updated: 2015-05-29

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 169 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2009-04-30
• Study Completion Date: 2014-03-31

Brief Summary

This study is designed to investigate the effects of two levels of resistance weight training on body composition, energy expenditure, and energy intake in men and women. The weight training will take about one hour to complete. Participants will perform the training 3 days per week for 9 months in a private exercise room equipped with state of the art equipment and a personal trainer to help guide you through the exercises.

The project lasts 21 months total with one follow-up visit 1-year from your last training date. You will be required to stay in the Lawrence area and train 3 day/week over the summer & holidays.

Detailed Description

We propose to conduct a randomized controlled efficacy trial (RT-1 set vs. RT-3 sets vs. non exercise control) to evaluate the potential for a longer intervention (9 months RT with body composition assessments 1 yr post RT completion) with a higher volume of RT (3 sets) to enhance the effects on body composition and energy expenditure observed in the pilot, and to determine the impact of the 2 levels of RT on free-living energy balance (expenditure by doubly labeled water and intake by digital photography and 24-hr recalls). This investigation will be conducted in a sample of healthy, normal and overweight, sedentary, young adult men and women; a group at high risk for development of overweight and obesity. The specific aims of this project are to determine the impact of the volume (1 vs. 3 sets) of a progressive RT protocol for inducing muscular hypertrophy, as recommended by the American College of Sports Medicine, on body weight and body composition (fat mass, fat-free mass (FFM), % body fat) and energy balance. Our results will provide information relative to the minimum volume of RT that may be associated with body weight/fat gain which may inform the development of guidelines for RT to prevent weight gain or to alter body composition. If RT has a favorable impact on energy balance and body composition, it may provide an attractive alternative to aerobic exercise for weight management for busy young adults, as RT requires minimal time, and no need to change clothes or shower (i.e. minimal or no sweating).

Conditions

Obesity

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Resistance training

1 set of progressive resistance training per session

Group Type: EXPERIMENTAL

Amount of resistance offered in training

Intervention Type: OTHER

to determine the impact of the volume (1 vs. 3 sets) of a progressive resistance training protocol for inducing muscular hypertrophy

3 sets per session

3 sets of progressive resistance training per session

Group Type: EXPERIMENTAL

Amount of resistance offered in training

Intervention Type: OTHER

to determine the impact of the volume (1 vs. 3 sets) of a progressive resistance training protocol for inducing muscular hypertrophy

Control

Non exercise control group

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Amount of resistance offered in training

to determine the impact of the volume (1 vs. 3 sets) of a progressive resistance training protocol for inducing muscular hypertrophy

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• BMI 22-<30
• 18- 30 years old
• sedentary
• no medications
• weight stable for at least 3 months

Exclusion Criteria

• Tobacco/Drug user
• metabolism altering medication
• gain/lost 10lbs in the last 3 months
• current exerciser

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role: collaborator

University of Kansas

OTHER

Sponsor Role: lead

Responsible Party

Richard Washburn

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Richard A Washburn, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Kansas

Locations

Energy Balance Lab, The University of Kansas

Lawrence, Kansas, United States

Countries

United States

Other Identifiers

NIDDKRO180832

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

HSCL17623

Identifier Type: -

Identifier Source: org_study_id