Effect of Different Protein Diets on Glucose and Insulin Metabolism and Substrate Partitioning

NCT ID: NCT01034241

Last Updated: 2018-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-04-30

Study Completion Date

2010-03-31

Brief Summary

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The purpose of this study is to determine whether different protein diets affects glucose and insulin metabolism and substrate partitioning.

Detailed Description

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Conditions

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Insulin Glucose Metabolism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Control

Diet consists of 15% dairy protein and low Glycemic Index (GI \< 40), 55 En% carbohydrates and 30 En% fat

Group Type EXPERIMENTAL

Control

Intervention Type DIETARY_SUPPLEMENT

Diet consists of 15 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat

High dairy protein

Diet consists of 25% dairy protein and low GI (GI \< 40), 45 En% carbohydrates and 30 En% fat

Group Type EXPERIMENTAL

High dairy protein

Intervention Type DIETARY_SUPPLEMENT

Diet consists of 25 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat

vegetable protein

Diet consists of 15 En% vegetable protein and low GI (GI \< 40), 55 En% carbohydrates and 30 En% fat

Group Type EXPERIMENTAL

vegetable protein

Intervention Type DIETARY_SUPPLEMENT

Diet consists of 15 En% vegetable protein and low GI, 55 En% carbohydrates and 30 En% fat

High GI

Diet consists of 15 En% dairy protein and high GI(GI \> 60, 55 En% carbohydrates and 30 En% fat

Group Type EXPERIMENTAL

High GI

Intervention Type DIETARY_SUPPLEMENT

Diet consists of 15 En% dairy protein and high GI, 55 En% carbohydrates and 30 En% fat

Interventions

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Control

Diet consists of 15 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat

Intervention Type DIETARY_SUPPLEMENT

High dairy protein

Diet consists of 25 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat

Intervention Type DIETARY_SUPPLEMENT

vegetable protein

Diet consists of 15 En% vegetable protein and low GI, 55 En% carbohydrates and 30 En% fat

Intervention Type DIETARY_SUPPLEMENT

High GI

Diet consists of 15 En% dairy protein and high GI, 55 En% carbohydrates and 30 En% fat

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* BMI: 18.5-25 kg/m2 (lean)
* Gender: Male
* Age: \<35 years
* Caucasian

Exclusion Criteria

* Elevated fasting blood glucose level
* Lactose intolerant
* Diabetes Mellitus
* Hypertension (systolic/diastolic blood pressure)
* Hypotension (systolic/diastolic blood pressure)
* Cardiovascular diseases
* Asthma and other obstructive pulmonary diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Nederlandse Zuivel Organisatie

OTHER

Sponsor Role collaborator

Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Wim Saris, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

Maastricht University

References

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Munsters MJ, Geraedts MC, Saris WH. Effects of different protein and glycemic index diets on metabolic profiles and substrate partitioning in lean healthy males. Appl Physiol Nutr Metab. 2013 Nov;38(11):1107-14. doi: 10.1139/apnm-2012-0409. Epub 2013 Apr 25.

Reference Type DERIVED
PMID: 24053517 (View on PubMed)

Other Identifiers

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MEC 08-3-072

Identifier Type: -

Identifier Source: org_study_id

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