Laparoscopic or Conventional Mesh Repair of Incisional and Umbilical Hernia

NCT ID: NCT00970515

Last Updated: 2021-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-11-30

Study Completion Date

2013-04-30

Brief Summary

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The aim of this study is to compare immediate and long-term (24 months) results of laparoscopic and open mesh repair of incisional and umbilical hernia.

Detailed Description

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The aim of this study is to compare immediate and long-term (24 months) results of laparoscopic and open mesh repair of incisional and umbilical hernia.

Five hundred patients will be included in this randomized, multicentric trial.

Hypotheses are that laparoscopic approach: 1- reduces immediate parietal complications without increasing intra abdominal septic complications 2- is less invasive and also reduces patients' hospital stay and recovery time; 3- has the same efficacy, than open approach.

Conditions

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Incisional Hernia Umbilical Hernia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Laparoscopic approach

group A: Laparoscopic approach

Group Type EXPERIMENTAL

Laparoscopic mesh hernia repair

Intervention Type PROCEDURE

The mesh is intraperitoneal

Open approach

group B: Open anterior approach

Group Type ACTIVE_COMPARATOR

Open anterior approach

Intervention Type PROCEDURE

The mesh is placed by an anterior approach. It is placed after incision of the skin over or under the abdominal muscles, or is intraperitoneal

Interventions

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Laparoscopic mesh hernia repair

The mesh is intraperitoneal

Intervention Type PROCEDURE

Open anterior approach

The mesh is placed by an anterior approach. It is placed after incision of the skin over or under the abdominal muscles, or is intraperitoneal

Intervention Type PROCEDURE

Other Intervention Names

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laparoscpic mesh repair of incisional and umbilical hernia Conventional treatment of incisional and umbilical hernia

Eligibility Criteria

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Inclusion Criteria

* Age \> 18
* Incisional or umbilical hernia over 2 cm and less than 6 cm in diameter

Exclusion Criteria

* Patients with a complicated incisional (pain, occlusion, cutaneous necrosis), irreductible painless incisional or umbilical hernia will not be considered as a complication
* Patients with a recurrence of incisional hernia
* Patients with an incisional or umbilical hernia whose lateral edges are located so that fixation of the mesh (which must extend beyond the 4 to 5 cm) is not possible
* Pregnant women
* Patients with HIV therapy
* Patients with cirrhotic ascites or other signs of hepatic insufficiency (bilirubin\> 35 micromol / l; TP \< 55%) or significant thrombocytopenia (\< 60 000 platelets)
* Patients with a contra indication for laparoscopy
* Patients with a life expectancy \< one year, or whose mobility within two years of treatment will damage proper monitoring
* Patients unable to understand information about the protocol
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Corinne Ms Vons, MD

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Locations

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Hôpital Jean Verdier, department of digestive and general surgery

Bondy, , France

Site Status

Countries

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France

References

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Slim K, Vons C. [Inguinal hernia repair: results of randomized clinical trials and meta-analyses]. J Chir (Paris). 2008 Mar-Apr;145(2):122-5. doi: 10.1016/s0021-7697(08)73720-7. French.

Reference Type BACKGROUND
PMID: 18645551 (View on PubMed)

Vons C. [Laparoscopic treatment of ventral hernias]. J Chir (Paris). 2004 Nov;141(6):366-70. doi: 10.1016/s0021-7697(04)95361-6. No abstract available. French.

Reference Type BACKGROUND
PMID: 15738845 (View on PubMed)

Proske JM, Vons C. [Laparoscopic treatment of ventral hernias]. J Chir (Paris). 2004 Nov;141(6):360-4. doi: 10.1016/s0021-7697(04)95360-4. French.

Reference Type BACKGROUND
PMID: 15738844 (View on PubMed)

Other Identifiers

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2007-A00374-49

Identifier Type: OTHER

Identifier Source: secondary_id

K060214

Identifier Type: -

Identifier Source: org_study_id

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